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SSX2IP and PKN1
Data Source:
BioGRID
(two hybrid)
SSX2IP
PKN1
Description
SSX family member 2 interacting protein
protein kinase N1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Adherens Junction
Cell Leading Edge
Protein-containing Complex
Centriolar Satellite
Ciliary Basal Body
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Cytosol
Midbody
Cleavage Furrow
Protein-containing Complex
Molecular Function
Protein Binding
Protein Domain Specific Binding
Chromatin Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Calcium-dependent Protein Kinase C Activity
Protein Kinase C Binding
Protein Binding
ATP Binding
Nuclear Receptor Coactivator Activity
Small GTPase Binding
Histone Kinase Activity (H3-T11 Specific)
Histone Binding
Histone Deacetylase Binding
Androgen Receptor Binding
Biological Process
Centrosome Cycle
Cell Adhesion
Regulation Of Rac Protein Signal Transduction
Intraciliary Transport Involved In Cilium Assembly
Cilium Assembly
Regulation Of Cell Motility
B Cell Homeostasis
B Cell Apoptotic Process
Regulation Of Germinal Center Formation
Regulation Of Immunoglobulin Production
Renal System Process
Regulation Of Transcription By RNA Polymerase II
Protein Phosphorylation
Negative Regulation Of Protein Kinase Activity
Hyperosmotic Response
Signal Transduction
Activation Of JUN Kinase Activity
Epithelial Cell Migration
Peptidyl-serine Phosphorylation
Negative Regulation Of B Cell Proliferation
Histone H3-T11 Phosphorylation
Intracellular Signal Transduction
Positive Regulation Of Transcription, DNA-templated
Spleen Development
Regulation Of Cell Motility
Pathways
RHO GTPases activate PKNs
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Drugs
Fostamatinib
Diseases
GWAS
Urinary albumin-to-creatinine ratio in non-diabetics (
26631737
)
Waist-to-hip ratio adjusted for body mass index (
28430825
)
Pancreatic cancer (
30206226
)
Urolithiasis (
30975718
)
Interacting Genes
113 interacting genes:
ABLIM3
ACTN1
ACTN2
AEN
AFDN
AP1M1
ARNT2
BCL6
BEX2
BRCA1
BYSL
C11orf54
CARD9
CCDC187
CCDC198
CCHCR1
CCNH
CDC23
CDC42
CDCA7L
CHCHD3
DAXX
DRG1
DVL2
EAF2
EHHADH
EIF4A2
ERAL1
FAM124B
FAM161A
FAM214A
FANCG
FANCL
FBF1
FNDC11
FRMD6
GEM
GOLGA2
GOLGA8F
GRAP2
HDAC4
HNRNPLL
IKBKG
INO80B
KAT5
KDM1A
KIF9
KIFC3
KLHL42
KRT15
KRT31
KRT40
KRTAP10-7
LATS1
LMO2
MCM7
MFAP1
MORN4
MOS
MRPL53
NAA10
NDN
NIF3L1
NOL12
NTAQ1
PHC2
PIMREG
PKN1
PNMA1
POLL
PRKAA1
PRKAB2
PRMT6
PRPF3
PRPF31
PSMA1
RNF6
SCNM1
SHFL
SSX2
SSX3
SYT17
TBP
TEAD4
TFIP11
TOP3B
TRIM42
TRIM54
TSGA10IP
TSTD2
TTC23
WDR5
XIAP
YWHAQ
YWHAZ
ZBTB24
ZFYVE26
ZGPAT
ZMAT2
ZNF124
ZNF202
ZNF250
ZNF3
ZNF408
ZNF417
ZNF438
ZNF587
ZNF648
ZNF688
ZNF71
ZNF792
ZRSR2
ZSCAN12
83 interacting genes:
ACTN1
ADAMTSL4
AKAP9
ARHGAP10
ARHGAP26
ARSA
BLZF1
BUD23
CASP3
CCDC103
CCDC136
CCDC138
CCDC85B
CCNT2
CD44
CDC25C
CDR2
CEP57
CEP57L1
CEP70
CYSRT1
DISC1
DYDC1
EIF3F
GOLGA2
GOLGA6L9
H3C14
HAP1
HAUS1
HDAC5
HOMER3
HSF2BP
INTS11
KIAA1328
KRT15
KRT16
KRT19
KRT31
KRT34
KRT35
KRT36
KRT37
LRRC61
MAP2K6
MAPK12
MAPT
MARCKS
MBP
MID1
MID2
MIPOL1
MKRN3
MTDH
MTUS2
NEFH
NEFL
NEUROD2
PDPK1
PICK1
PLD1
PNMA1
POU6F2
PSMB4
RAB3IP
RHOA
SERTAD3
SMYD3
SPAG5
SPRR2D
SSX2IP
STX11
SYCE3
TNFRSF1B
TRAF1
TRAF2
TRIM27
TSGA10
UBR2
USHBP1
VIM
ZFAND6
ZNF282
ZRANB1
Entrez ID
117178
5585
HPRD ID
10566
03019
Ensembl ID
ENSG00000117155
ENSG00000123143
Uniprot IDs
B7ZB07
Q9Y2D8
Q16512
PDB IDs
1CXZ
1URF
2RMK
4NKG
4OTD
4OTG
4OTH
4OTI
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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