TOP3B and PNMA2

		TOP3B	PNMA2
Description		DNA topoisomerase III beta	PNMA family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Nucleus	Nucleolus
	Molecular Function	DNA Binding RNA Binding DNA Topoisomerase Activity DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity Protein Binding	Protein Binding
	Biological Process	DNA Topological Change Chromosome Segregation	Positive Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Attention function in attention deficit hyperactive disorder ( 26174813) Bipolar disorder ( 31043756) Diastolic blood pressure ( 29208002) Response to selective serotonin reuptake inhibitors in depression ( 27622933)	Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		24 interacting genes: ADAMTSL4 AXIN2 BHLHB9 C1QBP CENPF CHD8 CHIC2 CIAO1 FASTK FBLN5 GRN KANK2 KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TRIM41 UPF2 ZFPM1 ZNF250 ZNF408	32 interacting genes: BYSL CBX8 CCDC33 CDC37 CNNM3 ENKD1 FAM161A GPATCH2L HAPLN2 INO80B LRR1 MISP MORF4L2 NTAQ1 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RTP5 SCNM1 SDCBP THAP7 TOP3B TTLL10 ZNF408 ZNF417 ZNF587 ZNF669 ZNF688 ZNF785
Entrez ID		8940	10687
HPRD ID		04662	04915
Ensembl ID		ENSG00000100038	ENSG00000240694
Uniprot IDs		A0A024R1C2 A8K4N2 O95985	Q5U5Z3 Q9UL42
PDB IDs		5GVC 5GVE
Enriched GO Terms of Interacting Partners?
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