TMEM106A and RHOU

Data Source:
BioGRID (pull down)

		TMEM106A	RHOU
Description		transmembrane protein 106A	ras homolog family member U
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Golgi Membrane Podosome Cytosol Plasma Membrane Focal Adhesion Cell Projection
	Molecular Function	Molecular_function Protein Binding	GTPase Activity Protein Binding GTP Binding Metal Ion Binding
	Biological Process	Biological_process Interleukin-1 Beta Production Interleukin-6 Production Tumor Necrosis Factor Production CD80 Biosynthetic Process CD86 Biosynthetic Process Macrophage Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process	Endocytosis Cytoskeleton Organization Regulation Of Cell Shape Cell Migration Cytokine-mediated Signaling Pathway Cell Projection Assembly Cdc42 Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Targeting To Mitochondrion
Pathways			Rho GTPase cycle Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Aging ( 22773346) Basal cell carcinoma ( 24403052 25855136 27539887 18849993) Chronic lymphocytic leukemia ( 28165464) Dental caries ( 23259602) Endometriosis ( 20844546) Leukoderma in response to rhododendrol ( 32558222) Mercury levels ( 26025379) Non-melanoma skin cancer ( 29739929) Response to antidepressants in depression ( 27622933) Type 2 diabetes ( 23300278)
Interacting Genes		13 interacting genes: ARF1 ENTPD3 ERG28 GJB2 GOSR2 IGFBP5 RHOU TMEM106C TMEM107 TMEM128 TMEM86B TNMD TSPAN4	128 interacting genes: ACAD8 ADM2 ALG13 ANGPT4 ANXA4 ANXA6 AP1S1 ARHGEF25 ARNTL AS3MT ATP5MG ATP6AP1 BDNF BNIPL BRF1 BRINP3 C14orf119 CDKL4 CFAP100 CHRNA4 CLEC7A CPNE3 CTCF CUL5 DACT2 DMRT2 DNM2 DOK4 DSCR8 EIF4B ELP5 EMC2 ERF ERO1A ESYT1 FAM110B FCHO2 FKBP15 GALNTL5 GLI3 GPRIN2 GRB2 H2BC14 HCAR1 HINT3 HSD17B13 ID2 IFFO1 IL17F INSM2 JAM3 KAAG1 KIAA1191 KLRC3 LANCL2 LARS2 LAYN LMO7 LYL1 MARCKS ME3 MOS MRAS MRPL15 NCK1 NCR1 NPM3 NR1H2 NRBF2 NXPH4 OXCT2 P4HTM PAK1 PAK4 PCDHGA4 PDLIM3 PGK1 PIP5K1A PLCG1 PLEK PLOD3 POT1 PRB1 PRPF18 PSMA4 PXN QTRT1 RAB40A RAD51D RALBP1 RASSF1 RBIS RPL23AP5 RPS15A RPS17P16 S100A4 SEC14L4 SEMA3G SEPTIN6 SIVA1 SKIV2L SLC26A1 SNU13 SOX4 SSC4D STX16 SYK TCN2 TEKT2 TMEM106A TMEM169 TMEM255B TRIM59 USP37 UTP3 VWA5A WNT6 XPA ZFAND2B ZFP64 ZKSCAN7 ZNF117 ZNF177 ZNF20 ZNF569 ZNF625 ZNF747 ZNF84
Entrez ID		113277	58480
HPRD ID		11315	06965
Ensembl ID		ENSG00000184988	ENSG00000116574
Uniprot IDs		B7Z779 Q96A25	A0A024R3Q7 Q7L0Q8
PDB IDs			2Q3H
Enriched GO Terms of Interacting Partners?
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