RHOU and AS3MT

RHOU

AS3MT

Description ras homolog family member U arsenite methyltransferase
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Arsenic metabolism ( 22383894 27352405)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood pressure ( 24954895)
  • Brain morphology (MOSTest) ( 32665545)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Coronary artery disease ( 29212778)
  • Diastolic blood pressure (long-term average) ( 28348047)
  • General risk tolerance (MTAG) ( 30643258)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure (long-term average) ( 28348047)
  • Mean reticulocyte volume ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Medication use (calcium channel blockers) ( 31015401)
  • Prostate cancer ( 23535732)
  • Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Red cell distribution width ( 32888494)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Schizophrenia ( 28991256 25056061 29483656 27922604 23974872 23894747)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Systolic blood pressure ( 19430483)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • White matter lesion progression ( 26451028)
Interacting Genes 128 interacting genes: ACAD8 ADM2 ALG13 ANGPT4 ANXA4 ANXA6 AP1S1 ARHGEF25 ARNTL AS3MT ATP5MG ATP6AP1 BDNF BNIPL BRF1 BRINP3 C14orf119 CDKL4 CFAP100 CHRNA4 CLEC7A CPNE3 CTCF CUL5 DACT2 DMRT2 DNM2 DOK4 DSCR8 EIF4B ELP5 EMC2 ERF ERO1A ESYT1 FAM110B FCHO2 FKBP15 GALNTL5 GLI3 GPRIN2 GRB2 H2BC14 HCAR1 HINT3 HSD17B13 ID2 IFFO1 IL17F INSM2 JAM3 KAAG1 KIAA1191 KLRC3 LANCL2 LARS2 LAYN LMO7 LYL1 MARCKS ME3 MOS MRAS MRPL15 NCK1 NCR1 NPM3 NR1H2 NRBF2 NXPH4 OXCT2 P4HTM PAK1 PAK4 PCDHGA4 PDLIM3 PGK1 PIP5K1A PLCG1 PLEK PLOD3 POT1 PRB1 PRPF18 PSMA4 PXN QTRT1 RAB40A RAD51D RALBP1 RASSF1 RBIS RPL23AP5 RPS15A RPS17P16 S100A4 SEC14L4 SEMA3G SEPTIN6 SIVA1 SKIV2L SLC26A1 SNU13 SOX4 SSC4D STX16 SYK TCN2 TEKT2 TMEM106A TMEM169 TMEM255B TRIM59 USP37 UTP3 VWA5A WNT6 XPA ZFAND2B ZFP64 ZKSCAN7 ZNF117 ZNF177 ZNF20 ZNF569 ZNF625 ZNF747 ZNF84 1 interacting genes: RHOU
Entrez ID 58480 57412
HPRD ID 06965 16511
Ensembl ID ENSG00000116574 ENSG00000214435
Uniprot IDs A0A024R3Q7 Q7L0Q8 Q9HBK9
PDB IDs 2Q3H
Enriched GO Terms of Interacting Partners?
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