TMEM106A and TMEM106C

Data Source:
BioGRID (two hybrid)

		TMEM106A	TMEM106C
Description		transmembrane protein 106A	transmembrane protein 106C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Cellular_component Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding	Molecular_function Protein Binding
	Biological Process	Biological_process Interleukin-1 Beta Production Interleukin-6 Production Tumor Necrosis Factor Production CD80 Biosynthetic Process CD86 Biosynthetic Process Macrophage Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process	Biological_process
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: ARF1 ENTPD3 ERG28 GJB2 GOSR2 IGFBP5 RHOU TMEM106C TMEM107 TMEM128 TMEM86B TNMD TSPAN4	42 interacting genes: ADAM33 AIG1 BNIP3 C14orf180 CLDN19 CMTM7 CTXN3 CXCL9 EDDM3B FAXDC2 GOSR2 HACD1 IGFBP5 JAGN1 KRT31 KRTAP10-3 MAL MARCHF2 MYADM NKG7 NRSN1 PGA4 PLN PLP1 PLPP6 PTTG1IP RPRM SEC22A SERP2 SFTPC SMAGP TMEM106A TMEM106B TMEM11 TMEM218 TMEM35A TMEM97 TSPAN33 UPK2 VAMP5 YIPF6 ZFPL1
Entrez ID		113277	79022
HPRD ID		11315	14690
Ensembl ID		ENSG00000184988	ENSG00000134291
Uniprot IDs		B7Z779 Q96A25	Q9BVX2
PDB IDs
Enriched GO Terms of Interacting Partners?
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