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RHOU and SOX4
Data Source:
BioGRID
(pull down)
RHOU
SOX4
Description
ras homolog family member U
SRY-box transcription factor 4
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Podosome
Cytosol
Plasma Membrane
Focal Adhesion
Cell Projection
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Mitochondrion
Molecular Function
GTPase Activity
Protein Binding
GTP Binding
Metal Ion Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
MiRNA Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Endocytosis
Cytoskeleton Organization
Regulation Of Cell Shape
Cell Migration
Cytokine-mediated Signaling Pathway
Cell Projection Assembly
Cdc42 Protein Signal Transduction
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Protein Targeting To Mitochondrion
Skeletal System Development
Neural Tube Formation
Pro-B Cell Differentiation
Mitral Valve Morphogenesis
Cardiac Ventricle Formation
Cardiac Right Ventricle Morphogenesis
Atrial Septum Primum Morphogenesis
Noradrenergic Neuron Differentiation
Regulation Of Transcription, DNA-templated
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Heart Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Anatomical Structure Morphogenesis
Glial Cell Proliferation
Spinal Cord Development
Spinal Cord Motor Neuron Differentiation
Glial Cell Development
Cell Differentiation
T Cell Differentiation
Endocrine Pancreas Development
Negative Regulation Of Protein Ubiquitination
Regulation Of Protein Stability
Positive Regulation Of Insulin Secretion
Somatic Stem Cell Population Maintenance
Ascending Aorta Morphogenesis
Glucose Homeostasis
DNA Damage Response, Detection Of DNA Damage
Positive Regulation Of Apoptotic Process
Positive Regulation Of Gamma-delta T Cell Differentiation
Positive Regulation Of Translation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Sympathetic Nervous System Development
Protein Stabilization
Limb Bud Formation
Ventricular Septum Morphogenesis
Negative Regulation Of Cell Death
Neuroepithelial Cell Differentiation
Kidney Morphogenesis
Hematopoietic Stem Cell Homeostasis
Cellular Response To Glucose Stimulus
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of N-terminal Peptidyl-lysine Acetylation
Pathways
Rho GTPase cycle
Interleukin-4 and Interleukin-13 signaling
Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS
Aging (
22773346
)
Basal cell carcinoma (
24403052
25855136
27539887
18849993
)
Chronic lymphocytic leukemia (
28165464
)
Dental caries (
23259602
)
Endometriosis (
20844546
)
Leukoderma in response to rhododendrol (
32558222
)
Mercury levels (
26025379
)
Non-melanoma skin cancer (
29739929
)
Response to antidepressants in depression (
27622933
)
Type 2 diabetes (
23300278
)
Bone mineral density (
21533022
)
Cardiac hypertrophy (
21348951
)
Endometrial cancer (
30093612
27008869
)
Endometrial cancer (endometrioid histology) (
30093612
)
Metabolite levels (
23823483
)
Pulmonary function (smoking interaction) (
23284291
)
Interacting Genes
128 interacting genes:
ACAD8
ADM2
ALG13
ANGPT4
ANXA4
ANXA6
AP1S1
ARHGEF25
ARNTL
AS3MT
ATP5MG
ATP6AP1
BDNF
BNIPL
BRF1
BRINP3
C14orf119
CDKL4
CFAP100
CHRNA4
CLEC7A
CPNE3
CTCF
CUL5
DACT2
DMRT2
DNM2
DOK4
DSCR8
EIF4B
ELP5
EMC2
ERF
ERO1A
ESYT1
FAM110B
FCHO2
FKBP15
GALNTL5
GLI3
GPRIN2
GRB2
H2BC14
HCAR1
HINT3
HSD17B13
ID2
IFFO1
IL17F
INSM2
JAM3
KAAG1
KIAA1191
KLRC3
LANCL2
LARS2
LAYN
LMO7
LYL1
MARCKS
ME3
MOS
MRAS
MRPL15
NCK1
NCR1
NPM3
NR1H2
NRBF2
NXPH4
OXCT2
P4HTM
PAK1
PAK4
PCDHGA4
PDLIM3
PGK1
PIP5K1A
PLCG1
PLEK
PLOD3
POT1
PRB1
PRPF18
PSMA4
PXN
QTRT1
RAB40A
RAD51D
RALBP1
RASSF1
RBIS
RPL23AP5
RPS15A
RPS17P16
S100A4
SEC14L4
SEMA3G
SEPTIN6
SIVA1
SKIV2L
SLC26A1
SNU13
SOX4
SSC4D
STX16
SYK
TCN2
TEKT2
TMEM106A
TMEM169
TMEM255B
TRIM59
USP37
UTP3
VWA5A
WNT6
XPA
ZFAND2B
ZFP64
ZKSCAN7
ZNF117
ZNF177
ZNF20
ZNF569
ZNF625
ZNF747
ZNF84
34 interacting genes:
AKT1
APOC3
AURKA
CAPN15
CDKN2A
CTR9
DACH1
EDF1
FOXH1
FZR1
IGF1
ITIH1
KRAS
MINPP1
MNT
MYC
NANOGNB
NF1
NF2
NSD3
PLD3
PLXNB1
RGSL1
RHOU
RP1L1
SCNN1G
SDCBP
SMARCA4
STK11
TERT
TNNI3
TSC1
UBE2I
WT1
Entrez ID
58480
6659
HPRD ID
06965
01695
Ensembl ID
ENSG00000116574
ENSG00000124766
Uniprot IDs
A0A024R3Q7
Q7L0Q8
Q06945
PDB IDs
2Q3H
Enriched GO Terms of Interacting Partners
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