FAM107A and NINL

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FAM107A	NINL
Description		family with sequence similarity 107 member A	ninein like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton Nuclear Speck Ruffle Membrane Neuron Projection Synapse	Centrosome Cytosol Microtubule Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	Molecular_function Actin Binding Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Regulation Of Cell Growth Cell Cycle Actin Filament Polymerization Positive Regulation Of Cell Migration Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Cellular Response To Nutrient Levels Regulation Of Actin Cytoskeleton Organization Cognition Actin Filament Bundle Assembly Negative Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Glucocorticoid Stimulus Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring At Centrosome Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917)	Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)
Interacting Genes		58 interacting genes: AGMAT APPBP2 AUH AZI2 BEGAIN BIRC8 CALCOCO2 CANX CCDC125 CCDC136 CCDC57 CCDC85B CPSF3 DAPK1 EFEMP2 EFHC2 EIF4A1 ESRRG FKBP6 FSD2 GFM2 GOLGA6L9 HFM1 HOOK2 HSF2BP HSPA14 HSPD1 HTRA1 IQUB ITPRID2 KRT15 KRT19 KRT27 KRT40 KRTAP4-12 LDOC1 LZTS2 MEIOB MID2 MTREX MTUS2 NEXN NFKBID NINL PLSCR1 PNMA1 POMP PSMD6 RAB18 RINT1 RNLS SPATA22 TADA2A TRAF2 TRIM37 USHBP1 VIM WDR47	51 interacting genes: AKAP17A APEX2 AURKB CBY2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA ERBB2 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 PRPF18 PRPF3 RBM41 RCOR3 RGS2 RIBC2 RNF40 SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646
Entrez ID		11170	22981
HPRD ID		09753	11120
Ensembl ID		ENSG00000168309	ENSG00000101004
Uniprot IDs		A0A024R327 O95990 Q6IAM1	Q9Y2I6
PDB IDs
Enriched GO Terms of Interacting Partners?
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