FAM107A and NEXN

Data Source:
BioGRID (two hybrid)

		FAM107A	NEXN
Description		family with sequence similarity 107 member A	nexilin F-actin binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton Nuclear Speck Ruffle Membrane Neuron Projection Synapse	Plasma Membrane Adherens Junction Focal Adhesion Actin Cytoskeleton Z Disc Axon
	Molecular Function	Molecular_function Actin Binding Protein Binding	Structural Constituent Of Muscle Actin Filament Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Regulation Of Cell Growth Cell Cycle Actin Filament Polymerization Positive Regulation Of Cell Migration Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Cellular Response To Nutrient Levels Regulation Of Actin Cytoskeleton Organization Cognition Actin Filament Bundle Assembly Negative Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Glucocorticoid Stimulus Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Regulation Of Cell Migration Regulation Of Cytoskeleton Organization Dendrite Self-avoidance
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917)	FEV1 ( 30804560) Lung cancer in never smokers ( 28604730) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		58 interacting genes: AGMAT APPBP2 AUH AZI2 BEGAIN BIRC8 CALCOCO2 CANX CCDC125 CCDC136 CCDC57 CCDC85B CPSF3 DAPK1 EFEMP2 EFHC2 EIF4A1 ESRRG FKBP6 FSD2 GFM2 GOLGA6L9 HFM1 HOOK2 HSF2BP HSPA14 HSPD1 HTRA1 IQUB ITPRID2 KRT15 KRT19 KRT27 KRT40 KRTAP4-12 LDOC1 LZTS2 MEIOB MID2 MTREX MTUS2 NEXN NFKBID NINL PLSCR1 PNMA1 POMP PSMD6 RAB18 RINT1 RNLS SPATA22 TADA2A TRAF2 TRIM37 USHBP1 VIM WDR47	11 interacting genes: ACTA1 CALM1 FAM107A FXR2 HMGB1 HMGB2 HSPB1 SIRPA TRIM15 ZNF250 ZSCAN22
Entrez ID		11170	91624
HPRD ID		09753	11388
Ensembl ID		ENSG00000168309	ENSG00000162614
Uniprot IDs		A0A024R327 O95990 Q6IAM1	B4DDI0 D3DQ79 Q0ZGT2
PDB IDs
Enriched GO Terms of Interacting Partners?
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