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GNB5 and TSC22D1
Data Source:
BioGRID
(two hybrid)
GNB5
TSC22D1
Description
G protein subunit beta 5
TSC22 domain family member 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Heterotrimeric G-protein Complex
Presynapse
GTPase Activator Complex
Nucleus
Cytoplasm
Molecular Function
GTPase Activity
GTPase Activator Activity
Protein Binding
G-protein Gamma-subunit Binding
Chaperone Binding
Protein Binding
Biological Process
Protein Folding
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Dopamine Receptor Signaling Pathway
Positive Regulation Of GTPase Activity
Negative Regulation Of Voltage-gated Calcium Channel Activity
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Pathways
Activation of G protein gated Potassium channels
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS
Lewy body disease (
25188341
)
Antineutrophil cytoplasmic antibody-associated vasculitis (
22808956
)
Body mass index (
25760438
)
Refractive error (
32231278
)
Rosacea symptom severity (
29771307
)
Interacting Genes
27 interacting genes:
ANXA7
APP
BNIP3L
CDKN1A
CSNK2B
DRD2
E2F2
EIF3J
GNG13
GNG2
GNG3
GNG4
GNG5
GNG7
GNGT1
MCM2
MVD
NR6A1
OLFM2
PSD
PSMD4
RGS11
RGS6
RGS7
RGS9
RPA1
TSC22D1
50 interacting genes:
A2M
APLP1
ASAH1
CACNA1A
CARHSP1
CCDC90B
CHD3
CORO2B
CRMP1
DDAH2
DNMT3B
EED
ERG28
FAF1
FAM20C
FBN3
GNB2
GNB5
GORASP2
HMGXB4
KMT2B
KMT2C
LRIF1
MAP3K12
MCM3AP
NCOA5
NTAQ1
OTUB1
PDHB
PRKCI
PTN
QARS1
RGS1
RPL5
SETDB1
SP110
SPACA9
SPRED1
TAF5L
TGFBR1
TLE1
TP53
TSC22D4
UBE2D1
UNC119
VIM
WDR73
WIZ
WNK1
ZC3HC1
Entrez ID
10681
8848
HPRD ID
09191
07414
Ensembl ID
ENSG00000069966
ENSG00000102804
Uniprot IDs
A0A024R5R9
A0A024R5V3
O14775
A0A024RDV8
A0A087X0H8
A8K3Y6
Q15714
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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