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GNB5 and RGS7
Data Source:
HPRD
(in vitro)
GNB5
RGS7
Description
G protein subunit beta 5
regulator of G protein signaling 7
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Heterotrimeric G-protein Complex
Presynapse
GTPase Activator Complex
Cytosol
Plasma Membrane
Molecular Function
GTPase Activity
GTPase Activator Activity
Protein Binding
G-protein Gamma-subunit Binding
Chaperone Binding
GTPase Activity
GTPase Activator Activity
G-protein Beta-subunit Binding
Biological Process
Protein Folding
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Dopamine Receptor Signaling Pathway
Positive Regulation Of GTPase Activity
Negative Regulation Of Voltage-gated Calcium Channel Activity
Protein Folding
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Intracellular Signal Transduction
Positive Regulation Of GTPase Activity
Pathways
Activation of G protein gated Potassium channels
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
G alpha (i) signalling events
G alpha (i) signalling events
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS
Lewy body disease (
25188341
)
Chronotype (
30696823
)
Diastolic blood pressure (
29208002
)
Ischemic stroke (cardioembolic) (
29531354
)
Longevity (90 years and older) (
25199915
)
Major depressive disorder (
27479909
)
Obesity-related traits (
23251661
)
Post bronchodilator FEV1 (
26634245
)
Western dietary pattern (
28644415
)
Interacting Genes
27 interacting genes:
ANXA7
APP
BNIP3L
CDKN1A
CSNK2B
DRD2
E2F2
EIF3J
GNG13
GNG2
GNG3
GNG4
GNG5
GNG7
GNGT1
MCM2
MVD
NR6A1
OLFM2
PSD
PSMD4
RGS11
RGS6
RGS7
RGS9
RPA1
TSC22D1
16 interacting genes:
CHRM1
CHRM2
CHRM3
CHRM5
GNAI1
GNAI3
GNAO1
GNAQ
GNAZ
GNB5
MSX1
PKD1
PRKCA
SNAPIN
YWHAB
YWHAQ
Entrez ID
10681
6000
HPRD ID
09191
03948
Ensembl ID
ENSG00000069966
ENSG00000182901
Uniprot IDs
A0A024R5R9
A0A024R5V3
O14775
B7Z223
B7Z257
P49802
PDB IDs
2A72
2D9J
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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