TSC22D1 and ASAH1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TSC22D1	ASAH1
Description		TSC22 domain family member 1	N-acylsphingosine amidohydrolase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Region Extracellular Space Nucleus Lysosome Early Endosome Endoplasmic Reticulum Lysosomal Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding	Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides N-acylsphingosine Amidohydrolase Activity Fatty Acid Amide Hydrolase Activity Ceramidase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II	Fatty Acid Metabolic Process Glycosphingolipid Metabolic Process Keratinocyte Differentiation Neutrophil Degranulation Sphingosine Biosynthetic Process Ceramide Biosynthetic Process Ceramide Catabolic Process Regulation Of Steroid Biosynthetic Process Regulation Of Programmed Necrotic Cell Death Cellular Response To Tumor Necrosis Factor
Pathways			Glycosphingolipid metabolism Neutrophil degranulation
Drugs
Diseases			Farber lipogranulomatosis; Farber disease
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Body mass index ( 25760438) Refractive error ( 32231278) Rosacea symptom severity ( 29771307)	Atrial fibrillation ( 28416818 30061737 29892015) Night sleep phenotypes ( 27126917) Obesity ( 21552555) Type 2 diabetes ( 32499647)
Interacting Genes		50 interacting genes: A2M APLP1 ASAH1 CACNA1A CARHSP1 CCDC90B CHD3 CORO2B CRMP1 DDAH2 DNMT3B EED ERG28 FAF1 FAM20C FBN3 GNB2 GNB5 GORASP2 HMGXB4 KMT2B KMT2C LRIF1 MAP3K12 MCM3AP NCOA5 NTAQ1 OTUB1 PDHB PRKCI PTN QARS1 RGS1 RPL5 SETDB1 SP110 SPACA9 SPRED1 TAF5L TGFBR1 TLE1 TP53 TSC22D4 UBE2D1 UNC119 VIM WDR73 WIZ WNK1 ZC3HC1	6 interacting genes: CAMK1D HSPB2 SETDB1 SMPD1 SRPK1 TSC22D1
Entrez ID		8848	427
HPRD ID		07414	01969
Ensembl ID		ENSG00000102804	ENSG00000104763
Uniprot IDs		A0A024RDV8 A0A087X0H8 A8K3Y6 Q15714	A8K0B6 Q13510 Q53H01
PDB IDs			5U7Z 6MHM
Enriched GO Terms of Interacting Partners?
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