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GNB5 and GNGT1
Data Source:
HPRD
(two hybrid)
GNB5
GNGT1
Description
G protein subunit beta 5
G protein subunit gamma transducin 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Heterotrimeric G-protein Complex
Presynapse
GTPase Activator Complex
Photoreceptor Inner Segment
Heterotrimeric G-protein Complex
Plasma Membrane
G-protein Beta/gamma-subunit Complex
Photoreceptor Disc Membrane
Molecular Function
GTPase Activity
GTPase Activator Activity
Protein Binding
G-protein Gamma-subunit Binding
Chaperone Binding
GTPase Activity
Protein Binding
G-protein Beta-subunit Binding
Biological Process
Protein Folding
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Dopamine Receptor Signaling Pathway
Positive Regulation Of GTPase Activity
Negative Regulation Of Voltage-gated Calcium Channel Activity
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Protein Localization
Cardiac Muscle Cell Apoptotic Process
Rhodopsin Mediated Signaling Pathway
Eye Photoreceptor Cell Development
Cellular Response To Hypoxia
Pathways
Activation of G protein gated Potassium channels
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Activation of G protein gated Potassium channels
G-protein activation
Activation of the phototransduction cascade
Activation of the phototransduction cascade
Inactivation, recovery and regulation of the phototransduction cascade
Inactivation, recovery and regulation of the phototransduction cascade
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Olfactory Signaling Pathway
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS
Lewy body disease (
25188341
)
Body mass index (
28552196
)
Body size at age 10 (
32376654
)
Heart rate response to recovery post exercise (10 sec) (
29497042
)
Heart rate response to recovery post exercise (20 sec) (
29497042
)
Heart rate response to recovery post exercise (30 sec) (
29497042
)
Heart rate response to recovery post exercise (40 sec) (
29497042
)
Heart rate response to recovery post exercise (50 sec) (
29497042
)
Mosquito bite size (
28199695
)
Resting heart rate (
29769521
27798624
)
Taxane-induced peripheral neuropathy in breast cancer (
29278617
)
Interacting Genes
27 interacting genes:
ANXA7
APP
BNIP3L
CDKN1A
CSNK2B
DRD2
E2F2
EIF3J
GNG13
GNG2
GNG3
GNG4
GNG5
GNG7
GNGT1
MCM2
MVD
NR6A1
OLFM2
PSD
PSMD4
RGS11
RGS6
RGS7
RGS9
RPA1
TSC22D1
14 interacting genes:
GNAS
GNB1
GNB2
GNB4
GNB5
GORASP2
IKBKG
MSANTD4
NAGA
PDCL
PLEKHB1
RHO
UBXN4
ZNF277
Entrez ID
10681
2792
HPRD ID
09191
01805
Ensembl ID
ENSG00000069966
ENSG00000127928
Uniprot IDs
A0A024R5R9
A0A024R5V3
O14775
P63211
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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