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TSC22D1 and PRKCI
Data Source:
BioGRID
(two hybrid)
TSC22D1
PRKCI
Description
TSC22 domain family member 1
protein kinase C iota
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Golgi Membrane
Nucleus
Nucleoplasm
Endosome
Cytosol
Plasma Membrane
Bicellular Tight Junction
Microtubule Cytoskeleton
Apical Plasma Membrane
Cell Leading Edge
Schmidt-Lanterman Incisure
Intercellular Bridge
Extracellular Exosome
Schaffer Collateral - CA1 Synapse
Glutamatergic Synapse
Molecular Function
Protein Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Kinase C Activity
Calcium-dependent Protein Kinase C Activity
Protein Binding
ATP Binding
Phospholipid Binding
Metal Ion Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Protein Phosphorylation
Protein Targeting To Membrane
Cytoskeleton Organization
Actin Filament Organization
Positive Regulation Of Neuron Projection Development
Vesicle-mediated Transport
Cell Migration
Peptidyl-serine Phosphorylation
Cellular Response To Insulin Stimulus
Negative Regulation Of Glial Cell Apoptotic Process
Establishment Of Apical/basal Cell Polarity
Intracellular Signal Transduction
Eye Photoreceptor Cell Development
Negative Regulation Of Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Cell-cell Junction Organization
Positive Regulation Of Notch Signaling Pathway
Positive Regulation Of Glucose Import
Secretion
Golgi Vesicle Budding
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Glial Cell Proliferation
Membrane Organization
Response To Interleukin-1
Bicellular Tight Junction Assembly
Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways
Pre-NOTCH Transcription and Translation
p75NTR recruits signalling complexes
Tight junction interactions
Drugs
Tamoxifen
Bisindolylmaleimide I
Fostamatinib
Diseases
GWAS
Antineutrophil cytoplasmic antibody-associated vasculitis (
22808956
)
Body mass index (
25760438
)
Refractive error (
32231278
)
Rosacea symptom severity (
29771307
)
Microalbuminuria (
31511532
)
Prostate cancer (
25939597
)
Urinary albumin excretion (
30220432
)
Urinary albumin-to-creatinine ratio (
31630189
31511532
)
Interacting Genes
50 interacting genes:
A2M
APLP1
ASAH1
CACNA1A
CARHSP1
CCDC90B
CHD3
CORO2B
CRMP1
DDAH2
DNMT3B
EED
ERG28
FAF1
FAM20C
FBN3
GNB2
GNB5
GORASP2
HMGXB4
KMT2B
KMT2C
LRIF1
MAP3K12
MCM3AP
NCOA5
NTAQ1
OTUB1
PDHB
PRKCI
PTN
QARS1
RGS1
RPL5
SETDB1
SP110
SPACA9
SPRED1
TAF5L
TGFBR1
TLE1
TP53
TSC22D4
UBE2D1
UNC119
VIM
WDR73
WIZ
WNK1
ZC3HC1
52 interacting genes:
ADAP1
ANXA1
APP
BAD
CASK
CASP8
CCNT1
CDC42
CDK7
CHUK
CTBP1
FABP4
FCGR3A
FRS2
FRS3
GAPDH
HRAS
IKBKG
IL1RAP
IRAK1
MAP2K1
MAP2K5
MAPT
MARK4
MBP
MEOX2
NACC1
NFKBIA
PARD3
PARD6A
PARD6B
PARD6G
PCM1
PDPK1
PNMA1
RAB2A
RAB4A
RAC1
RBM14
RHOQ
RPA2
SMG1
SMURF1
SQSTM1
SRC
TSC22D1
TTR
UBC
USP20
VHL
YWHAH
YWHAZ
Entrez ID
8848
5584
HPRD ID
07414
02105
Ensembl ID
ENSG00000102804
ENSG00000163558
Uniprot IDs
A0A024RDV8
A0A087X0H8
A8K3Y6
Q15714
P41743
PDB IDs
1VD2
1WMH
1ZRZ
3A8W
3A8X
3ZH8
5LI1
5LI9
5LIH
6ILZ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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