Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
CEBPB and ATF2
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro)
CEBPB
ATF2
Description
CCAAT enhancer binding protein beta
activating transcription factor 2
Image
GO Annotations
Cellular Component
Condensed Chromosome, Centromeric Region
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
CHOP-C/EBP Complex
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Outer Membrane
Site Of Double-strand Break
H4 Histone Acetyltransferase Complex
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Kinase Binding
Histone Acetyltransferase Binding
Glucocorticoid Receptor Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Ubiquitin-like Protein Ligase Binding
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Activating Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
DNA-binding Transcription Factor Activity
Histone Acetyltransferase Activity
Protein Binding
CAMP Response Element Binding Protein Binding
H4 Histone Acetyltransferase Activity
Protein Kinase Binding
CAMP Response Element Binding
H2B Histone Acetyltransferase Activity
Protein-containing Complex Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Ovarian Follicle Development
Embryonic Placenta Development
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Acute-phase Response
Inflammatory Response
Immune Response
Memory
Neuron Differentiation
Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-4 Production
Mammary Gland Epithelial Cell Proliferation
Response To Endoplasmic Reticulum Stress
Negative Regulation Of T Cell Proliferation
Defense Response To Bacterium
Negative Regulation Of Neuron Apoptotic Process
Regulation Of Cell Differentiation
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Regulation Of Osteoclast Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Inflammatory Response
Brown Fat Cell Differentiation
Mammary Gland Epithelial Cell Differentiation
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Biomineral Tissue Development
Cellular Response To Lipopolysaccharide
Cellular Response To Amino Acid Stimulus
Cellular Response To Interleukin-1
Cellular Response To Organic Cyclic Compound
Hepatocyte Proliferation
Liver Regeneration
Positive Regulation Of Cold-induced Thermogenesis
Regulation Of Odontoblast Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Sodium-dependent Phosphate Transport
Regulation Of Dendritic Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
Outflow Tract Morphogenesis
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Response To Osmotic Stress
Cellular Response To DNA Damage Stimulus
Response To Water Deprivation
Positive Regulation Of Gene Expression
Negative Regulation Of Angiogenesis
Intra-S DNA Damage Checkpoint
Positive Regulation Of Transforming Growth Factor Beta2 Production
Positive Regulation Of Neuron Apoptotic Process
Histone H4 Acetylation
Histone H2B Acetylation
Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Epithelial Cell Proliferation
Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of DNA-binding Transcription Factor Activity
Adipose Tissue Development
Amelogenesis
Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Pathways
Senescence-Associated Secretory Phenotype (SASP)
Senescence-Associated Secretory Phenotype (SASP)
ATF4 activates genes in response to endoplasmic reticulum stress
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Transcriptional Regulation by VENTX
Transcriptional regulation of granulopoiesis
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Transcriptional activation of mitochondrial biogenesis
HATs acetylate histones
Circadian Clock
Activation of the AP-1 family of transcription factors
TP53 Regulates Transcription of DNA Repair Genes
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Estrogen-dependent gene expression
NGF-stimulated transcription
NGF-stimulated transcription
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK4 (GCN2) to amino acid deficiency
Drugs
Quercetin
Pseudoephedrine
Diseases
GWAS
Bronchodilator response in asthma (
25562107
)
Gut microbiota (functional units) (
27694959
)
Inflammatory bowel disease (
23128233
)
Meconium ileus in cystic fibrosis (
30807572
)
Type 2 diabetes (
30297969
32499647
30718926
)
Intake of total sugars (
31005972
)
Metabolite levels (
23823483
)
Interacting Genes
57 interacting genes:
AR
ATF2
ATF4
CAMK2A
CCL3
CCNT1
CDK9
CEBPA
CEBPD
CEBPG
CREB1
CREBBP
DDIT3
EGFR
EGR1
ELK1
EP300
ESR1
FOXO1
HMGA1
HMGB1
HNRNPK
HOMER3
HSF1
KAT2A
KAT2B
MAPK1
MAPK3
MED23
MYB
MYC
NCOR2
NFKB1
NOLC1
NR3C1
PTGES2
RARB
RB1
RELA
RPS6KA1
RPS6KA5
RUNX1
RUNX2
SMAD3
SMAD4
SMARCA4
SMARCB1
SMARCC1
SP1
SPI1
SPIB
SRF
STAT5A
STAT6
TAF9
TRIB1
TRIM28
63 interacting genes:
APP
AR
ATF3
ATF4
ATF7
BACH1
BANP
BATF
CCDC6
CCND1
CEBPA
CEBPB
CEBPG
CENPQ
CREB5
CSNK2A1
CSNK2A2
DDIT3
DNMT3L
EDF1
ETS1
EXOSC8
FOS
FOSB
FOSL1
FOSL2
GTF2F2
H2BC21
HMGA1
IRF2BP1
JDP2
JUN
KIFC3
LHX8
MACROH2A1
MAPK1
MAPK10
MAPK11
MAPK13
MAPK14
MAPK8
MAPK9
MAPKAPK5
MLH1
NBN
NCOA6
PIAS2
PML
PRKCE
RB1
RNF4
RPS6KA5
RUVBL2
SMAD3
SMAD4
SPOPL
SRA1
SUMO1
THRB
UBE2I
UTF1
XPO1
YY1
Entrez ID
1051
1386
HPRD ID
01801
00443
Ensembl ID
ENSG00000172216
ENSG00000115966
Uniprot IDs
P17676
A4D7V5
P15336
PDB IDs
1GTW
1GU4
1GU5
1H88
1H89
1H8A
1HJB
1IO4
2E42
2E43
6MG1
6MG2
6MG3
1BHI
1T2K
4H36
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?