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CEBPB and EGR1
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
CEBPB
EGR1
Description
CCAAT enhancer binding protein beta
early growth response 1
Image
GO Annotations
Cellular Component
Condensed Chromosome, Centromeric Region
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
CHOP-C/EBP Complex
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Kinase Binding
Histone Acetyltransferase Binding
Glucocorticoid Receptor Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Ubiquitin-like Protein Ligase Binding
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Double-stranded Methylated DNA Binding
Histone Acetyltransferase Binding
Sequence-specific DNA Binding
Hemi-methylated DNA-binding
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Ovarian Follicle Development
Embryonic Placenta Development
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Acute-phase Response
Inflammatory Response
Immune Response
Memory
Neuron Differentiation
Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-4 Production
Mammary Gland Epithelial Cell Proliferation
Response To Endoplasmic Reticulum Stress
Negative Regulation Of T Cell Proliferation
Defense Response To Bacterium
Negative Regulation Of Neuron Apoptotic Process
Regulation Of Cell Differentiation
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Regulation Of Osteoclast Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Inflammatory Response
Brown Fat Cell Differentiation
Mammary Gland Epithelial Cell Differentiation
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Biomineral Tissue Development
Cellular Response To Lipopolysaccharide
Cellular Response To Amino Acid Stimulus
Cellular Response To Interleukin-1
Cellular Response To Organic Cyclic Compound
Hepatocyte Proliferation
Liver Regeneration
Positive Regulation Of Cold-induced Thermogenesis
Regulation Of Odontoblast Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Sodium-dependent Phosphate Transport
Regulation Of Dendritic Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
Response To Hypoxia
Response To Ischemia
Regulation Of Transcription By RNA Polymerase II
Response To Glucose
Positive Regulation Of Gene Expression
T Cell Differentiation
BMP Signaling Pathway
Positive Regulation Of Chemokine Production
Positive Regulation Of Interleukin-1 Beta Production
Response To Insulin
Circadian Regulation Of Gene Expression
Regulation Of Protein Sumoylation
Skeletal Muscle Cell Differentiation
Regulation Of Apoptotic Process
Estrous Cycle
Locomotor Rhythm
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Hormone Biosynthetic Process
Circadian Temperature Homeostasis
Type I Interferon Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Interleukin-1-mediated Signaling Pathway
Cellular Response To Gamma Radiation
Cellular Response To Heparin
Cellular Response To Mycophenolic Acid
Glomerular Mesangial Cell Proliferation
Positive Regulation Of Glomerular Metanephric Mesangial Cell Proliferation
Negative Regulation Of Canonical Wnt Signaling Pathway
Cellular Response To Interleukin-8
Positive Regulation Of Neuron Death
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Positive Regulation Of Tau-protein Kinase Activity
Regulation Of Progesterone Biosynthetic Process
Pathways
Senescence-Associated Secretory Phenotype (SASP)
Senescence-Associated Secretory Phenotype (SASP)
ATF4 activates genes in response to endoplasmic reticulum stress
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Transcriptional Regulation by VENTX
Transcriptional regulation of granulopoiesis
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
NGF-stimulated transcription
NGF-stimulated transcription
Interferon alpha/beta signaling
Drugs
Quercetin
Diseases
GWAS
Bronchodilator response in asthma (
25562107
)
Gut microbiota (functional units) (
27694959
)
Inflammatory bowel disease (
23128233
)
Meconium ileus in cystic fibrosis (
30807572
)
Type 2 diabetes (
30297969
32499647
30718926
)
Amyotrophic lateral sclerosis (C9orf72 mutation interaction) (
22959728
)
Autism spectrum disorder or schizophrenia (
28540026
)
Cerebrospinal AB1-42 levels in Alzheimer's disease dementia (
29274321
)
Schizophrenia (
28991256
25056061
)
Interacting Genes
57 interacting genes:
AR
ATF2
ATF4
CAMK2A
CCL3
CCNT1
CDK9
CEBPA
CEBPD
CEBPG
CREB1
CREBBP
DDIT3
EGFR
EGR1
ELK1
EP300
ESR1
FOXO1
HMGA1
HMGB1
HNRNPK
HOMER3
HSF1
KAT2A
KAT2B
MAPK1
MAPK3
MED23
MYB
MYC
NCOR2
NFKB1
NOLC1
NR3C1
PTGES2
RARB
RB1
RELA
RPS6KA1
RPS6KA5
RUNX1
RUNX2
SMAD3
SMAD4
SMARCA4
SMARCB1
SMARCC1
SP1
SPI1
SPIB
SRF
STAT5A
STAT6
TAF9
TRIB1
TRIM28
23 interacting genes:
CDKN2A
CEBPB
CRBN
CREBBP
CSNK2A1
DNMT3L
EP300
ERBB3
IL1B
JUN
MTDH
NAB1
NAB2
NFATC1
NFATC2
PITX1
PSMA3
RELA
SP1
SRA1
SREBF2
TP53
WT1
Entrez ID
1051
1958
HPRD ID
01801
00549
Ensembl ID
ENSG00000172216
ENSG00000120738
Uniprot IDs
P17676
P18146
Q546S1
PDB IDs
1GTW
1GU4
1GU5
1H88
1H89
1H8A
1HJB
1IO4
2E42
2E43
6MG1
6MG2
6MG3
4R2A
4R2C
4R2D
4X9J
5N14
Enriched GO Terms of Interacting Partners
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