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CEBPB and HSF1
Data Source:
BioGRID
(pull down)
HPRD
(in vitro, in vivo)
CEBPB
HSF1
Description
CCAAT enhancer binding protein beta
heat shock transcription factor 1
Image
GO Annotations
Cellular Component
Condensed Chromosome, Centromeric Region
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
CHOP-C/EBP Complex
Kinetochore
Condensed Chromosome Kinetochore
Chromatin
Euchromatin
Heterochromatin
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
PML Body
Perinuclear Region Of Cytoplasm
Nuclear Stress Granule
Mitotic Spindle Pole
Chaperone Complex
Ribonucleoprotein Complex
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Kinase Binding
Histone Acetyltransferase Binding
Glucocorticoid Receptor Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Ubiquitin-like Protein Ligase Binding
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Protein Kinase Binding
Heat Shock Protein Binding
Chromatin DNA Binding
Identical Protein Binding
Sequence-specific DNA Binding
Protein Self-association
Protein Heterodimerization Activity
Hsp90 Protein Binding
Translation Elongation Factor Binding
STAT Family Protein Binding
Sequence-specific Single Stranded DNA Binding
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Ovarian Follicle Development
Embryonic Placenta Development
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Acute-phase Response
Inflammatory Response
Immune Response
Memory
Neuron Differentiation
Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-4 Production
Mammary Gland Epithelial Cell Proliferation
Response To Endoplasmic Reticulum Stress
Negative Regulation Of T Cell Proliferation
Defense Response To Bacterium
Negative Regulation Of Neuron Apoptotic Process
Regulation Of Cell Differentiation
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Regulation Of Osteoclast Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Inflammatory Response
Brown Fat Cell Differentiation
Mammary Gland Epithelial Cell Differentiation
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Biomineral Tissue Development
Cellular Response To Lipopolysaccharide
Cellular Response To Amino Acid Stimulus
Cellular Response To Interleukin-1
Cellular Response To Organic Cyclic Compound
Hepatocyte Proliferation
Liver Regeneration
Positive Regulation Of Cold-induced Thermogenesis
Regulation Of Odontoblast Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Sodium-dependent Phosphate Transport
Regulation Of Dendritic Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
MAPK Cascade
DNA Repair
Regulation Of Transcription By RNA Polymerase II
MRNA Processing
Defense Response
Response To Nutrient
Positive Regulation Of Cell Population Proliferation
MRNA Transcription
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Response To Activity
Viral Process
Negative Regulation Of Protein-containing Complex Assembly
Response To Testosterone
Cellular Response To Heat
Cellular Response To Unfolded Protein
Cellular Protein-containing Complex Assembly
Cellular Response To Potassium Ion
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Mitotic Cell Cycle
Positive Regulation Of Transcription By RNA Polymerase II
MRNA Transport
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Heat Stress
Cellular Response To Hydrogen Peroxide
Cellular Response To Lipopolysaccharide
Cellular Response To Cadmium Ion
Cellular Response To Copper Ion
Cellular Response To Estradiol Stimulus
Cellular Response To Gamma Radiation
Cellular Response To Diamide
Negative Regulation Of Inclusion Body Assembly
Positive Regulation Of Inclusion Body Assembly
Positive Regulation Of Cold-induced Thermogenesis
Regulation Of Cellular Response To Heat
Positive Regulation Of MRNA Polyadenylation
Negative Regulation Of Neuron Death
Positive Regulation Of Apoptotic DNA Fragmentation
Cellular Response To Sodium Arsenite
Cellular Response To Angiotensin
Positive Regulation Of Microtubule Binding
Cellular Response To Nitroglycerin
Cellular Response To L-glutamine
Response To Hypobaric Hypoxia
Response To Psychosocial Stress
Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
Senescence-Associated Secretory Phenotype (SASP)
Senescence-Associated Secretory Phenotype (SASP)
ATF4 activates genes in response to endoplasmic reticulum stress
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Transcriptional Regulation by VENTX
Transcriptional regulation of granulopoiesis
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Regulation of HSF1-mediated heat shock response
HSF1 activation
Attenuation phase
HSF1-dependent transactivation
Aggrephagy
Drugs
Quercetin
Bimoclomol
Diseases
GWAS
Bronchodilator response in asthma (
25562107
)
Gut microbiota (functional units) (
27694959
)
Inflammatory bowel disease (
23128233
)
Meconium ileus in cystic fibrosis (
30807572
)
Type 2 diabetes (
30297969
32499647
30718926
)
Dupuytren's disease (
28886342
)
Interacting Genes
57 interacting genes:
AR
ATF2
ATF4
CAMK2A
CCL3
CCNT1
CDK9
CEBPA
CEBPD
CEBPG
CREB1
CREBBP
DDIT3
EGFR
EGR1
ELK1
EP300
ESR1
FOXO1
HMGA1
HMGB1
HNRNPK
HOMER3
HSF1
KAT2A
KAT2B
MAPK1
MAPK3
MED23
MYB
MYC
NCOR2
NFKB1
NOLC1
NR3C1
PTGES2
RARB
RB1
RELA
RPS6KA1
RPS6KA5
RUNX1
RUNX2
SMAD3
SMAD4
SMARCA4
SMARCB1
SMARCC1
SP1
SPI1
SPIB
SRF
STAT5A
STAT6
TAF9
TRIB1
TRIM28
51 interacting genes:
CAMK2A
CDC20
CDK6
CEBPB
CHST10
CREBBP
CSNK2A1
DAXX
DNAJB1
EEF1D
ENO2
FILIP1
FKBP4
FKBP5
GSK3A
GTF2A2
GTF2B
HSBP1
HSF2
HSP90AA1
HSP90AB1
HSPA1A
HSPA8
MAPK1
MAPK3
MAPK8
MAPK9
MAPKAPK2
NCOA6
PIM2
PPID
PRKDC
PTGES3
RALBP1
REPS1
RNF20
SMARCA4
STAT1
STUB1
SUB1
SUMO1
SUMO3
SYMPK
TAF1
TAF7
TAF9
TBP
UBE2I
XRCC5
XRCC6
YWHAE
Entrez ID
1051
3297
HPRD ID
01801
00778
Ensembl ID
ENSG00000172216
ENSG00000185122
Uniprot IDs
P17676
Q00613
PDB IDs
1GTW
1GU4
1GU5
1H88
1H89
1H8A
1HJB
1IO4
2E42
2E43
6MG1
6MG2
6MG3
2LDU
5D5U
5D5V
5HDG
5HDN
Enriched GO Terms of Interacting Partners
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