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CEBPB and SRF
Data Source:
HPRD
(in vivo, in vitro)
CEBPB
SRF
Description
CCAAT enhancer binding protein beta
serum response factor
Image
GO Annotations
Cellular Component
Condensed Chromosome, Centromeric Region
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
CHOP-C/EBP Complex
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Kinase Binding
Histone Acetyltransferase Binding
Glucocorticoid Receptor Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Ubiquitin-like Protein Ligase Binding
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Serum Response Element Binding
Chromatin DNA Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Primary MiRNA Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Ovarian Follicle Development
Embryonic Placenta Development
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Acute-phase Response
Inflammatory Response
Immune Response
Memory
Neuron Differentiation
Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-4 Production
Mammary Gland Epithelial Cell Proliferation
Response To Endoplasmic Reticulum Stress
Negative Regulation Of T Cell Proliferation
Defense Response To Bacterium
Negative Regulation Of Neuron Apoptotic Process
Regulation Of Cell Differentiation
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Regulation Of Osteoclast Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Inflammatory Response
Brown Fat Cell Differentiation
Mammary Gland Epithelial Cell Differentiation
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Biomineral Tissue Development
Cellular Response To Lipopolysaccharide
Cellular Response To Amino Acid Stimulus
Cellular Response To Interleukin-1
Cellular Response To Organic Cyclic Compound
Hepatocyte Proliferation
Liver Regeneration
Positive Regulation Of Cold-induced Thermogenesis
Regulation Of Odontoblast Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Sodium-dependent Phosphate Transport
Regulation Of Dendritic Cell Differentiation
Branching Involved In Blood Vessel Morphogenesis
Response To Hypoxia
Mesoderm Formation
Neuron Migration
Trophectodermal Cell Differentiation
Heart Looping
Morphogenesis Of An Epithelial Sheet
Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation
Regulation Of Transcription By RNA Polymerase II
Cell-matrix Adhesion
Heart Development
Long-term Memory
Negative Regulation Of Cell Population Proliferation
Associative Learning
Response To Toxic Substance
Response To Hormone
Epithelial Structure Maintenance
Positive Regulation Of Transcription Via Serum Response Element Binding
Hippocampus Development
Tangential Migration From The Subventricular Zone To The Olfactory Bulb
Actin Cytoskeleton Organization
Regulation Of Cell Adhesion
Platelet Activation
Platelet Formation
Negative Regulation Of Cell Migration
Thyroid Gland Development
Neuron Projection Development
Regulation Of Water Loss Via Skin
Response To Cytokine
Megakaryocyte Development
Dorsal Aorta Morphogenesis
Stress Fiber Assembly
Skin Morphogenesis
Positive Thymic T Cell Selection
Sarcomere Organization
Positive Regulation Of Cell Differentiation
Positive Regulation Of Axon Extension
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Smooth Muscle Contraction
Positive Regulation Of Transcription By Glucose
Muscle Cell Cellular Homeostasis
Thymus Development
Developmental Growth
Neuron Development
Erythrocyte Development
Positive Regulation Of DNA-binding Transcription Factor Activity
Regulation Of Smooth Muscle Cell Differentiation
Positive Regulation Of Filopodium Assembly
Cardiac Myofibril Assembly
Angiogenesis Involved In Wound Healing
Hematopoietic Stem Cell Differentiation
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Long-term Synaptic Depression
Face Development
Heart Trabecula Formation
Lung Morphogenesis
Bronchus Cartilage Development
Trachea Cartilage Development
Cardiac Vascular Smooth Muscle Cell Differentiation
Eyelid Development In Camera-type Eye
Lung Smooth Muscle Development
Bicellular Tight Junction Assembly
Cellular Response To Glucose Stimulus
Primitive Streak Formation
Epithelial Cell-cell Adhesion
Cellular Senescence
Negative Regulation Of Amyloid-beta Clearance
Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Pathways
Senescence-Associated Secretory Phenotype (SASP)
Senescence-Associated Secretory Phenotype (SASP)
ATF4 activates genes in response to endoplasmic reticulum stress
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Transcriptional Regulation by VENTX
Transcriptional regulation of granulopoiesis
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Response of EIF2AK1 (HRI) to heme deficiency
RHO GTPases Activate Formins
NGF-stimulated transcription
NGF-stimulated transcription
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Drugs
Quercetin
Diseases
GWAS
Bronchodilator response in asthma (
25562107
)
Gut microbiota (functional units) (
27694959
)
Inflammatory bowel disease (
23128233
)
Meconium ileus in cystic fibrosis (
30807572
)
Type 2 diabetes (
30297969
32499647
30718926
)
Interacting Genes
57 interacting genes:
AR
ATF2
ATF4
CAMK2A
CCL3
CCNT1
CDK9
CEBPA
CEBPD
CEBPG
CREB1
CREBBP
DDIT3
EGFR
EGR1
ELK1
EP300
ESR1
FOXO1
HMGA1
HMGB1
HNRNPK
HOMER3
HSF1
KAT2A
KAT2B
MAPK1
MAPK3
MED23
MYB
MYC
NCOR2
NFKB1
NOLC1
NR3C1
PTGES2
RARB
RB1
RELA
RPS6KA1
RPS6KA5
RUNX1
RUNX2
SMAD3
SMAD4
SMARCA4
SMARCB1
SMARCC1
SP1
SPI1
SPIB
SRF
STAT5A
STAT6
TAF9
TRIB1
TRIM28
71 interacting genes:
ALDH3A1
ATF6
BARX2
CAMK2A
CASP3
CASP6
CASP7
CASP8
CASP9
CD63
CEBPB
CIRBP
CREB1
CREBBP
CRIP2
CSNK2A1
ELK1
ELK4
ETV4
FHL1
FHL2
FHL3
FHL5
FLI1
FOXG1
FOXK1
GATA4
GTF2F1
GTF2I
HDAC4
HMGA1
HOPX
KAT5
KDM6A
MAPKAPK2
MINPP1
MRTFA
MRTFB
MYOCD
MYOD1
MYOG
NCOA1
NCOA6
NCOR2
NFKB1
NFYA
NKX2-3
NKX2-5
NKX3-1
OGT
PML
PRKDC
PRRX1
PYCARD
RARA
REL
RELA
RPS6KA1
RXRA
RXRG
SHBG
SP1
SRC
SRFBP1
SSRP1
TCF3
TEAD1
TRIM63
TRIP4
UBE2I
ZIC3
Entrez ID
1051
6722
HPRD ID
01801
02788
Ensembl ID
ENSG00000172216
ENSG00000112658
Uniprot IDs
P17676
A0A024RD16
B4DU24
P11831
PDB IDs
1GTW
1GU4
1GU5
1H88
1H89
1H8A
1HJB
1IO4
2E42
2E43
6MG1
6MG2
6MG3
1HBX
1K6O
1SRS
Enriched GO Terms of Interacting Partners
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