PPIH and LNX2

Data Source:
BioGRID (two hybrid)

		PPIH	LNX2
Description		peptidylprolyl isomerase H	ligand of numb-protein X 2
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Ribonucleoprotein Complex Binding	Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding Positive Regulation Of Viral Genome Replication Protein-containing Complex Assembly
Pathways		mRNA Splicing - Major Pathway
Drugs		Proline
Diseases
GWAS			Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		13 interacting genes: BAG2 BPIFA1 DOK3 LNX1 LNX2 N4BP2L2 NIF3L1 PRPF18 PRPF31 PRPF4 SNU13 UBQLN2 XIAP	89 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581
Entrez ID		10465	222484
HPRD ID		12084	10042
Ensembl ID		ENSG00000171960	ENSG00000139517
Uniprot IDs		O43447 Q6FH36	Q8N448
PDB IDs		1MZW 1QOI 5O9Z 6AHD	2VWR 5DIN 5E11 5E1Y 5E21 5E22
Enriched GO Terms of Interacting Partners?
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