PPIH and DOK3

Data Source:
BioGRID (two hybrid)

		PPIH	DOK3
Description		peptidylprolyl isomerase H	docking protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP	Plasma Membrane Secretory Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Ribonucleoprotein Complex Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding Positive Regulation Of Viral Genome Replication Protein-containing Complex Assembly	Neutrophil Degranulation
Pathways		mRNA Splicing - Major Pathway	Neutrophil degranulation
Drugs		Proline
Diseases
GWAS			Coronary artery disease ( 29212778) Inflammatory bowel disease ( 23128233) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		13 interacting genes: BAG2 BPIFA1 DOK3 LNX1 LNX2 N4BP2L2 NIF3L1 PRPF18 PRPF31 PRPF4 SNU13 UBQLN2 XIAP	31 interacting genes: A1CF ABL1 ANKS1A APPL1 APPL2 COX5B CRK CSK DOK1 DOK2 DOK5 DTX2 FYN GCM2 HOXA1 INPP5D LCK LYN MDFI PLEKHA3 PPIH PRKAB2 RBPMS RET RIN3 SHC3 SHE SPAG8 STAT3 TNS2 TRAF1
Entrez ID		10465	79930
HPRD ID		12084	16834
Ensembl ID		ENSG00000171960	ENSG00000146094
Uniprot IDs		O43447 Q6FH36	A0A024R7M5 A0A6M4C8X9 D6RAM3 Q7L591
PDB IDs		1MZW 1QOI 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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