LNX2 and RBM17

Data Source:
BioGRID (two hybrid)

		LNX2	RBM17
Description		ligand of numb-protein X 2	RNA binding motif protein 17
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GO Annotations	Cellular Component		Nucleoplasm Spliceosomal Complex
	Molecular Function	Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding	RNA Binding Protein Binding
	Biological Process		Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 31619474) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Brooding (response to stress) ( 30886212) Crohn's disease ( 28067908) Diisocyanate-induced asthma ( 25918132) Multiple sclerosis ( 24076602) Soluble interleukin-2 receptor subunit alpha ( 26293465) Vitiligo ( 20410501)
Interacting Genes		89 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581	27 interacting genes: APBB1 CCDC170 CCHCR1 CEP55 CSNK2A1 CWC15 DHX15 FAM9B GOLGA2 HINFP HSF2BP IQCN LNX2 MIR106B MIR107 MIR128-1 MIR155 MIR21 MIR25 MIRLET7A2 MIRLET7G MIRLET7I PPP1R12C QRICH1 SAP30BP SAT1 SF1
Entrez ID		222484	84991
HPRD ID		10042	09501
Ensembl ID		ENSG00000139517	ENSG00000134453
Uniprot IDs		Q8N448	Q5W009 Q96I25
PDB IDs		2VWR 5DIN 5E11 5E1Y 5E21 5E22	2PE8 2PEH 5LSO 6HIP
Enriched GO Terms of Interacting Partners?
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