PPIH and BAG2

Data Source:
BioGRID (two hybrid, two hybrid)

		PPIH	BAG2
Description		peptidylprolyl isomerase H	BAG cochaperone 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP	Cytosol Microtubule Axon Dendrite Chaperone Complex Dendritic Microtubule
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Ribonucleoprotein Complex Binding	Adenyl-nucleotide Exchange Factor Activity Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Ion Channel Binding Tau Protein Binding Chaperone Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding Positive Regulation Of Viral Genome Replication Protein-containing Complex Assembly	Protein Folding Positive Regulation Of Protein Processing Protein Metabolic Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Binding Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Cellular Response To Heat Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin Protein Ligase Activity
Pathways		mRNA Splicing - Major Pathway	Regulation of HSF1-mediated heat shock response
Drugs		Proline
Diseases
GWAS
Interacting Genes		13 interacting genes: BAG2 BPIFA1 DOK3 LNX1 LNX2 N4BP2L2 NIF3L1 PRPF18 PRPF31 PRPF4 SNU13 UBQLN2 XIAP	17 interacting genes: CCAR2 DAPK1 DISC1 DNAJC6 HSPA1A HSPA4 HSPA8 LRRK1 LRRK2 MAPKAPK2 MFHAS1 NOTCH3 PINK1 PPIH SLU7 WDR77 WDR83
Entrez ID		10465	9532
HPRD ID		12084	04859
Ensembl ID		ENSG00000171960	ENSG00000112208
Uniprot IDs		O43447 Q6FH36	O95816
PDB IDs		1MZW 1QOI 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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