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SEC24B and SEC23A
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
SEC24B
SEC23A
Description
SEC24 homolog B, COPII coat complex component
SEC23 homolog A, COPII coat complex component
Image
GO Annotations
Cellular Component
Golgi Membrane
Endoplasmic Reticulum Membrane
Cytosol
ER To Golgi Transport Vesicle Membrane
COPII Vesicle Coat
Endoplasmic Reticulum Exit Site
Golgi Membrane
Endoplasmic Reticulum Membrane
Cytosol
ER To Golgi Transport Vesicle Membrane
Extrinsic Component Of Membrane
COPII Vesicle Coat
Perinuclear Region Of Cytoplasm
Endoplasmic Reticulum Exit Site
Molecular Function
SNARE Binding
Protein Binding
Zinc Ion Binding
GTPase Activator Activity
Protein Binding
Zinc Ion Binding
Biological Process
Neural Tube Closure
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Outflow Tract Morphogenesis
Intracellular Protein Transport
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Cochlear Nucleus Development
Aorta Morphogenesis
COPII Vesicle Coating
Auditory Receptor Cell Stereocilium Organization
Lung Lobe Morphogenesis
Coronary Artery Morphogenesis
Pulmonary Artery Morphogenesis
COPII-coated Vesicle Cargo Loading
Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure
Regulation Of Cargo Loading Into COPII-coated Vesicle
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Intracellular Protein Transport
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of GTPase Activity
COPII Vesicle Coating
Protein Localization To Plasma Membrane
COPII-coated Vesicle Cargo Loading
Pathways
Regulation of cholesterol biosynthesis by SREBP (SREBF)
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Regulation of cholesterol biosynthesis by SREBP (SREBF)
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
Cranio-lenticulo-sutural dysplasia (CLSD); Boyadjiev-Jabs syndrome
GWAS
Late-onset Alzheimer's disease (
27770636
)
Metabolite levels (
23823483
)
Vitamin D levels (
29343764
)
Interacting Genes
2 interacting genes:
SCAP
SEC23A
35 interacting genes:
BNIP3
CADPS
CDK16
CDK18
CLEC17A
DCTN1
DNM2
DTX2
ERGIC3
ERLIN1
FASLG
FATE1
GJA8
GLRA2
HOMEZ
MFF
MIA2
MIA3
MINAR1
NDRG1
PIAS2
RNF19B
SDCBP2
SEC16A
SEC23B
SEC23IP
SEC24B
SEC24C
SEC24D
SF1
SLC7A1
SUCLA2
TMEM45B
TNFSF14
WBP11
Entrez ID
10427
10484
HPRD ID
06216
06714
Ensembl ID
ENSG00000138802
ENSG00000100934
Uniprot IDs
B4DTM6
O95487
Q15436
PDB IDs
3EH1
2NUP
2NUT
2YRC
2YRD
3EFO
3EG9
3EGD
3EGX
5KYN
5KYU
5KYW
5KYX
5KYY
5VNE
5VNF
5VNG
5VNH
5VNI
5VNJ
5VNK
5VNL
5VNM
5VNN
5VNO
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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