MPHOSPH6 and GDF9

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MPHOSPH6	GDF9
Description		M-phase phosphoprotein 6	growth differentiation factor 9
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytosol	Extracellular Space Cytoplasm
	Molecular Function	RNA Binding Protein Binding	Cytokine Activity Growth Factor Activity Type I Activin Receptor Binding
	Biological Process	Maturation Of 5.8S RRNA RRNA Processing	Oocyte Growth Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth BMP Signaling Pathway SMAD Protein Signal Transduction Regulation Of Progesterone Secretion
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Leukocyte telomere length ( 32109421 31171785) Lung adenocarcinoma ( 28604730) Nevus count or cutaneous melanoma ( 32341527) Obesity-related traits ( 23251661) Seasonality and depression ( 30217971)	Asthma ( 31619474)
Interacting Genes		32 interacting genes: AATF APLP1 ARHGAP18 DNM2 DYNLRB1 EIF3G ERG28 EXOSC1 EXOSC10 EXOSC3 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL GDF9 HSPB1 KNSTRN LRIF1 MTREX NUPR1 PARN RBM48 RPS20 SMARCA4 SNX9 THOP1 TLE1 TP53 UNC119 ZHX1	45 interacting genes: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CDKN1A CDKN2C CRELD1 DLEU1 DNM2 FOXG1 FXYD6 GADD45G ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TDGF1 TK1 TRIB3 WASHC3
Entrez ID		10200	2661
HPRD ID		16111	03560
Ensembl ID		ENSG00000135698	ENSG00000164404
Uniprot IDs		H3BNT4 Q99547	B4DXG3 O60383
PDB IDs		6D6Q 6D6R 6H25
Enriched GO Terms of Interacting Partners?
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