TSPAN2 and MFF

Data Source:
BioGRID (two hybrid)

		TSPAN2	MFF
Description		tetraspanin 2	mitochondrial fission factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Integral Component Of Plasma Membrane Integral Component Of Membrane Myelin Sheath	Mitochondrion Mitochondrial Outer Membrane Peroxisome Synaptic Vesicle Integral Component Of Mitochondrial Outer Membrane Integral Component Of Mitochondrial Membrane Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Inflammatory Response Brain Development Astrocyte Development Microglia Development Myelination Oligodendrocyte Differentiation Axon Development	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Mitochondrial Fragmentation Involved In Apoptotic Process Mitochondrion Morphogenesis Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Targeting To Membrane Regulation Of Peroxisome Organization
Pathways
Drugs
Diseases
GWAS		Dysmenorrheic pain ( 27454463) Ischemic stroke (large artery atherosclerosis) ( 26708676 29531354) Large artery stroke (CCS and TOAST classification) ( 32047268) Large artery stroke (CCS or TOAST classification) ( 32047268) Large artery stroke (CCSp classification)j ( 32047268) Migraine ( 27182965 23793025 27322543) Migraine without aura ( 23793025 27322543)	Intraocular pressure ( 29617998) Refractive astigmatism ( 30306274)
Interacting Genes		35 interacting genes: ABHD16A ATP1B4 BSCL2 CD79A CLDN5 CLEC14A CREB3 CREB3L1 DCBLD2 FAM209A FKBP7 FOS GRB2 IFNGR2 KDELR3 LEPROTL1 LMNA MFF MGST3 PGRMC2 PIK3R3 RABGAP1L REEP4 RNF19B SCN3B SLC10A6 SLC30A8 SLC35C2 TMEM130 TMEM14B TMEM31 TMX2 TSPAN31 VSIR ZFYVE27	105 interacting genes: ADIPOQ AGPAT4 AIG1 ANKRD46 APOD APOL2 AQP3 AQP6 ATP6V0B BET1 C14orf180 C1QL4 C3orf52 CD79A CDIPT CEND1 CLDN19 CMTM5 CNIH1 COL4A5 CTXN3 CXCL16 CYB5B CYBC1 DNM1L ERGIC3 FAM209A FAM210B FAM3C FATE1 FCER1G FDCSP FXYD6 GJB1 GKN1 GOSR2 GPR152 IGFBP5 JAGN1 LAT LHFPL5 LPAR3 MEOX2 MIP MMGT1 MOSPD3 MPZL1 MTNR1B NIPAL3 NRM NTS OPN1SW OPRM1 PLK3 PLLP PLN PLP1 RAET1L RETREG3 RHBDL1 SACM1L SEC11C SEC22A SEC22B SEC23A SERINC2 SHISAL1 SLC18A3 SLC35B1 SLC41A2 SLC7A1 SLC7A14 SLC7A8 SMIM1 STRIT1 STX7 STX8 TEX264 TFRC TM6SF1 TMEM128 TMEM140 TMEM14C TMEM201 TMEM218 TMEM229B TMEM237 TMEM254 TMEM42 TMEM60 TMEM86B TMEM88 TMEM97 TMX2 TRAF3IP3 TRAM1L1 TRARG1 TSPAN2 TSPAN33 TSPO2 UNC50 UNC93B1 UPK1B VAMP4 ZFPL1
Entrez ID		10100	56947
HPRD ID		18233	16653
Ensembl ID		ENSG00000134198	ENSG00000168958
Uniprot IDs		B1AKP1 B2RD31 O60636	A0A0A0MS29 A1MAC2 Q9GZY8
PDB IDs
Enriched GO Terms of Interacting Partners?
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