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MFF and DNM1L
Data Source:
BioGRID
(proximity labelling technology, pull down)
MFF
DNM1L
Description
mitochondrial fission factor
dynamin 1 like
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Outer Membrane
Peroxisome
Synaptic Vesicle
Integral Component Of Mitochondrial Outer Membrane
Integral Component Of Mitochondrial Membrane
Protein-containing Complex
Golgi Membrane
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Peroxisome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Microtubule
Brush Border
Clathrin-coated Pit
Membrane
Synaptic Vesicle Membrane
Mitochondrial Membrane
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Presynaptic Endocytic Zone Membrane
Mitochondrion-derived Vesicle
Molecular Function
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
GTPase Activity
GTPase Activator Activity
Protein Binding
GTP Binding
Microtubule Binding
Lipid Binding
Clathrin Binding
GTP-dependent Protein Binding
Small GTPase Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein-containing Complex Binding
BH2 Domain Binding
Biological Process
Mitochondrial Fission
Release Of Cytochrome C From Mitochondria
Protein Targeting To Mitochondrion
Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Peroxisome Fission
Mitochondrial Fragmentation Involved In Apoptotic Process
Mitochondrion Morphogenesis
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Positive Regulation Of Protein Targeting To Membrane
Regulation Of Peroxisome Organization
Mitochondrial Fission
Release Of Cytochrome C From Mitochondria
Dynamin Family Protein Polymerization Involved In Mitochondrial Fission
Calcium Ion Transport
Mitochondrion Organization
Endoplasmic Reticulum Organization
Regulation Of Gene Expression
Negative Regulation Of Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Peroxisome Fission
Synaptic Vesicle Recycling Via Endosome
Positive Regulation Of Apoptotic Process
Positive Regulation Of GTPase Activity
Mitochondrial Fragmentation Involved In Apoptotic Process
Intracellular Distribution Of Mitochondria
Synaptic Vesicle Endocytosis
Rhythmic Process
Positive Regulation Of Protein Secretion
Protein Complex Oligomerization
Heart Contraction
Positive Regulation Of Dendritic Spine Morphogenesis
Membrane Fusion
Protein-containing Complex Assembly
Necroptotic Process
Mitochondrion Morphogenesis
Protein Localization To Mitochondrion
Positive Regulation Of Neutrophil Chemotaxis
Positive Regulation Of Mitochondrial Fission
Mitochondrial Membrane Fission
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Cellular Response To Oxygen-glucose Deprivation
Execution Phase Of Apoptosis
Regulation Of Peroxisome Organization
Positive Regulation Of Synaptic Vesicle Endocytosis
Regulation Of Autophagy Of Mitochondrion
Regulation Of ATP Metabolic Process
Cellular Response To Thapsigargin
Regulation Of Ubiquitin Protein Ligase Activity
Response To Flavonoid
Response To Hypobaric Hypoxia
Positive Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Apoptotic execution phase
Drugs
Diseases
GWAS
Intraocular pressure (
29617998
)
Refractive astigmatism (
30306274
)
Mean platelet volume (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
)
Interacting Genes
105 interacting genes:
ADIPOQ
AGPAT4
AIG1
ANKRD46
APOD
APOL2
AQP3
AQP6
ATP6V0B
BET1
C14orf180
C1QL4
C3orf52
CD79A
CDIPT
CEND1
CLDN19
CMTM5
CNIH1
COL4A5
CTXN3
CXCL16
CYB5B
CYBC1
DNM1L
ERGIC3
FAM209A
FAM210B
FAM3C
FATE1
FCER1G
FDCSP
FXYD6
GJB1
GKN1
GOSR2
GPR152
IGFBP5
JAGN1
LAT
LHFPL5
LPAR3
MEOX2
MIP
MMGT1
MOSPD3
MPZL1
MTNR1B
NIPAL3
NRM
NTS
OPN1SW
OPRM1
PLK3
PLLP
PLN
PLP1
RAET1L
RETREG3
RHBDL1
SACM1L
SEC11C
SEC22A
SEC22B
SEC23A
SERINC2
SHISAL1
SLC18A3
SLC35B1
SLC41A2
SLC7A1
SLC7A14
SLC7A8
SMIM1
STRIT1
STX7
STX8
TEX264
TFRC
TM6SF1
TMEM128
TMEM140
TMEM14C
TMEM201
TMEM218
TMEM229B
TMEM237
TMEM254
TMEM42
TMEM60
TMEM86B
TMEM88
TMEM97
TMX2
TRAF3IP3
TRAM1L1
TRARG1
TSPAN2
TSPAN33
TSPO2
UNC50
UNC93B1
UPK1B
VAMP4
ZFPL1
20 interacting genes:
FIS1
FZR1
GSK3B
MAGEA1
MAGEA3
MAP3K10
MFF
MIEF1
MIEF2
MUL1
PINK1
PRKN
RRM2
SCG3
SENP3
SH3GL1
SIRT3
SUMO2
VIM
ZBTB24
Entrez ID
56947
10059
HPRD ID
16653
04833
Ensembl ID
ENSG00000168958
ENSG00000087470
Uniprot IDs
A0A0A0MS29
A1MAC2
Q9GZY8
B4DYR6
O00429
PDB IDs
3W6N
3W6O
3W6P
4BEJ
4H1U
4H1V
5WP9
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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