TSPAN2 and CLEC14A

Data Source:
BioGRID (two hybrid)

		TSPAN2	CLEC14A
Description		tetraspanin 2	C-type lectin domain containing 14A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Integral Component Of Plasma Membrane Integral Component Of Membrane Myelin Sheath	External Side Of Plasma Membrane Integral Component Of Membrane Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding	Protein Binding Carbohydrate Binding Extracellular Matrix Binding Extracellular Matrix Protein Binding
	Biological Process	Inflammatory Response Brain Development Astrocyte Development Microglia Development Myelination Oligodendrocyte Differentiation Axon Development	Lymphangiogenesis Cell Migration Involved In Sprouting Angiogenesis Cell Migration Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Vascular Endothelial Growth Factor Receptor-3 Signaling Pathway
Pathways
Drugs			Resveratrol
Diseases
GWAS		Dysmenorrheic pain ( 27454463) Ischemic stroke (large artery atherosclerosis) ( 26708676 29531354) Large artery stroke (CCS and TOAST classification) ( 32047268) Large artery stroke (CCS or TOAST classification) ( 32047268) Large artery stroke (CCSp classification)j ( 32047268) Migraine ( 27182965 23793025 27322543) Migraine without aura ( 23793025 27322543)	Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Type 2 diabetes ( 30297969 32499647) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		35 interacting genes: ABHD16A ATP1B4 BSCL2 CD79A CLDN5 CLEC14A CREB3 CREB3L1 DCBLD2 FAM209A FKBP7 FOS GRB2 IFNGR2 KDELR3 LEPROTL1 LMNA MFF MGST3 PGRMC2 PIK3R3 RABGAP1L REEP4 RNF19B SCN3B SLC10A6 SLC30A8 SLC35C2 TMEM130 TMEM14B TMEM31 TMX2 TSPAN31 VSIR ZFYVE27	13 interacting genes: ATP6V0C CLDN19 CLDN4 CYB561D2 EMD LHFPL5 MALL MGST2 MS4A1 PMP22 TMEM243 TSPAN2 VAMP3
Entrez ID		10100	161198
HPRD ID		18233	10711
Ensembl ID		ENSG00000134198	ENSG00000176435
Uniprot IDs		B1AKP1 B2RD31 O60636	Q86T13
PDB IDs
Enriched GO Terms of Interacting Partners?
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