MFF and AGPAT4

Data Source:
BioGRID (two hybrid)

		MFF	AGPAT4
Description		mitochondrial fission factor	1-acylglycerol-3-phosphate O-acyltransferase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisome Synaptic Vesicle Integral Component Of Mitochondrial Outer Membrane Integral Component Of Mitochondrial Membrane Protein-containing Complex	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding Transferase Activity, Transferring Acyl Groups
	Biological Process	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Mitochondrial Fragmentation Involved In Apoptotic Process Mitochondrion Morphogenesis Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Targeting To Membrane Regulation Of Peroxisome Organization	Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process
Pathways			Synthesis of PA
Drugs
Diseases
GWAS		Intraocular pressure ( 29617998) Refractive astigmatism ( 30306274)	Anxiety in major depressive disorder ( 24047446) Diastolic blood pressure ( 30224653) Energy expenditure (24h) ( 28476931) Fear of pain ( 28701861) Lipoprotein (a) - cholesterol levels ( 25575512) Lipoprotein (a) levels ( 26377243) Metabolite levels ( 23823483)
Interacting Genes		105 interacting genes: ADIPOQ AGPAT4 AIG1 ANKRD46 APOD APOL2 AQP3 AQP6 ATP6V0B BET1 C14orf180 C1QL4 C3orf52 CD79A CDIPT CEND1 CLDN19 CMTM5 CNIH1 COL4A5 CTXN3 CXCL16 CYB5B CYBC1 DNM1L ERGIC3 FAM209A FAM210B FAM3C FATE1 FCER1G FDCSP FXYD6 GJB1 GKN1 GOSR2 GPR152 IGFBP5 JAGN1 LAT LHFPL5 LPAR3 MEOX2 MIP MMGT1 MOSPD3 MPZL1 MTNR1B NIPAL3 NRM NTS OPN1SW OPRM1 PLK3 PLLP PLN PLP1 RAET1L RETREG3 RHBDL1 SACM1L SEC11C SEC22A SEC22B SEC23A SERINC2 SHISAL1 SLC18A3 SLC35B1 SLC41A2 SLC7A1 SLC7A14 SLC7A8 SMIM1 STRIT1 STX7 STX8 TEX264 TFRC TM6SF1 TMEM128 TMEM140 TMEM14C TMEM201 TMEM218 TMEM229B TMEM237 TMEM254 TMEM42 TMEM60 TMEM86B TMEM88 TMEM97 TMX2 TRAF3IP3 TRAM1L1 TRARG1 TSPAN2 TSPAN33 TSPO2 UNC50 UNC93B1 UPK1B VAMP4 ZFPL1	28 interacting genes: AQP12B AQP6 CNR2 CREB3L1 ERGIC3 FCGR2A FCRL3 FFAR2 GPR101 HSD17B11 HSD17B13 JAGN1 LEPROTL1 LEUTX LRRC25 MFF MFSD14B MGST3 REEP4 REL RETREG3 SCN3B SLC35C2 SLC7A8 SPACA1 TMEM14B TMEM31 TMX2
Entrez ID		56947	56895
HPRD ID		16653	12437
Ensembl ID		ENSG00000168958	ENSG00000026652
Uniprot IDs		A0A0A0MS29 A1MAC2 Q9GZY8	Q9NRZ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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