TSPAN2 and ATP1B4

Data Source:
BioGRID (two hybrid)

		TSPAN2	ATP1B4
Description		tetraspanin 2	ATPase Na+/K+ transporting family member beta 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Integral Component Of Plasma Membrane Integral Component Of Membrane Myelin Sheath	Nuclear Envelope Nuclear Inner Membrane Integral Component Of Plasma Membrane Sodium:potassium-exchanging ATPase Complex
	Molecular Function	Protein Binding	Protein Binding Inorganic Cation Transmembrane Transporter Activity
	Biological Process	Inflammatory Response Brain Development Astrocyte Development Microglia Development Myelination Oligodendrocyte Differentiation Axon Development	Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Inorganic Cation Transmembrane Transport
Pathways			SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Drugs
Diseases
GWAS		Dysmenorrheic pain ( 27454463) Ischemic stroke (large artery atherosclerosis) ( 26708676 29531354) Large artery stroke (CCS and TOAST classification) ( 32047268) Large artery stroke (CCS or TOAST classification) ( 32047268) Large artery stroke (CCSp classification)j ( 32047268) Migraine ( 27182965 23793025 27322543) Migraine without aura ( 23793025 27322543)	Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		35 interacting genes: ABHD16A ATP1B4 BSCL2 CD79A CLDN5 CLEC14A CREB3 CREB3L1 DCBLD2 FAM209A FKBP7 FOS GRB2 IFNGR2 KDELR3 LEPROTL1 LMNA MFF MGST3 PGRMC2 PIK3R3 RABGAP1L REEP4 RNF19B SCN3B SLC10A6 SLC30A8 SLC35C2 TMEM130 TMEM14B TMEM31 TMX2 TSPAN31 VSIR ZFYVE27	7 interacting genes: ASGR1 C3orf52 CSGALNACT2 CXCL9 ERMP1 SMIM3 TSPAN2
Entrez ID		10100	23439
HPRD ID		18233	06453
Ensembl ID		ENSG00000134198	ENSG00000101892
Uniprot IDs		B1AKP1 B2RD31 O60636	Q9UN42
PDB IDs
Enriched GO Terms of Interacting Partners?
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