SLC9A3R1 and RLBP1

Number of citations of the paper that reports this interaction (PMID 14744877)
16

Data Source:
HPRD (in vitro)

		SLC9A3R1	RLBP1
Gene Name		solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	retinaldehyde binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Centrosome Plasma Membrane Microvillus Endomembrane System Actin Cytoskeleton Membrane Apical Plasma Membrane Filopodium Brush Border Membrane Microvillus Membrane Vesicle Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Vesicular Exosome Cell Periphery Sperm Midpiece	Cellular_component Cytosol Cell Body
	Molecular Function	Receptor Binding Protein Binding Beta-catenin Binding Chloride Channel Regulator Activity Phosphatase Binding PDZ Domain Binding Beta-2 Adrenergic Receptor Binding Protein Complex Binding Protein Complex Scaffold Protein Self-association Dopamine Receptor Binding Growth Factor Receptor Binding	Transporter Activity 11-cis Retinal Binding Retinol Binding
	Biological Process	Renal Sodium Ion Transport Protein Complex Assembly Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Wnt Signaling Pathway Microvillus Assembly Actin Cytoskeleton Organization Negative Regulation Of Cell Migration Cellular Phosphate Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium:proton Antiporter Activity Bile Acid Secretion Cellular Protein Localization Glutathione Transport Regulation Of Excretion Regulation Of Protein Kinase Activity Negative Regulation Of Protein Kinase B Signaling Phospholipase C-activating Dopamine Receptor Signaling Pathway Renal Absorption Negative Regulation Of ERK1 And ERK2 Cascade Renal Phosphate Ion Absorption Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Retinoid Metabolic Process Vitamin A Metabolic Process Transport Visual Perception Phototransduction, Visible Light
Pathways			Visual phototransduction The canonical retinoid cycle in rods (twilight vision) Retinoid cycle disease events Diseases associated with visual transduction The retinoid cycle in cones (daylight vision)
Drugs			Vitamin A
Diseases
GWAS		Fibrinogen ( 20031577)
Protein-Protein Interactions		52 interactors: ABCC2 ABCC4 ADRB2 AKAP10 ATP6V1B1 ATP6V1E1 BCL10 CFTR CLCN3 CNGA2 CTNNB1 EGFR EZR GNA11 GNAQ GRK6 KCNJ1 LHCGR LPAR2 MSN NF2 NOS2 OPRK1 P2RY1 PAG1 PDGFRA PDGFRB PDZK1 PIK3CA PLCB1 PLCB2 PTEN PTH1R RDX RLBP1 SCN4A SLC22A11 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC4A8 SLC9A3 SLCO1A2 SLCO3A1 TBC1D10A TRPC4 TRPC5 YAP1 YES1 ZNF468	3 interactors: APP RDH5 SLC9A3R1
Entrez ID		9368	6017
HPRD ID		05406	01572
Ensembl ID		ENSG00000109062	ENSG00000140522
Uniprot IDs		O14745	P12271
PDB IDs		1G9O 1GQ4 1GQ5 1I92 1SGH 2D10 2JXO 2KJD 2KRG 2M0T 2M0U 2M0V 2OZF	1XGG 1XGH 3HX3 3HY5
Enriched GO Terms of Interacting Partners?		Ion Homeostasis Ion Transmembrane Transport Transmembrane Transport Homeostatic Process Ion Transport Anion Transport Organic Anion Transport Anion Transmembrane Transport Chemical Homeostasis Cellular Ion Homeostasis Positive Regulation Of Phospholipase C Activity Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of PH Response To Organonitrogen Compound Cellular Chemical Homeostasis Monocarboxylic Acid Transport Positive Regulation Of Phospholipase Activity Transport Cellular Cation Homeostasis G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Vasodilation Regulation Of Phosphorus Metabolic Process Cellular Response To Organonitrogen Compound Response To Stimulus Inorganic Anion Transport Regulation Of Ion Transport Regulation Of Membrane Potential Cell Development Response To External Stimulus Monovalent Inorganic Cation Transport Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Metal Ion Transport Cellular Homeostasis Establishment Of Endothelial Barrier Regulation Of Ion Transmembrane Transport Blood Coagulation Response To Estrogen Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Hemostasis Regulation Of Body Fluid Levels Signaling Wound Healing Response To Organic Substance Response To Hormone Cell Surface Receptor Signaling Pathway Cell Communication Cation Transport Positive Regulation Of Inositol Phosphate Biosynthetic Process	Renal Phosphate Ion Absorption Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Renal Sodium Ion Transport Axon Midline Choice Point Recognition Response To Light Stimulus Alcohol Metabolic Process Cellular Phosphate Ion Homeostasis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Axon Choice Point Recognition Negative Regulation Of Sodium Ion Transmembrane Transport Phospholipase C-activating Dopamine Receptor Signaling Pathway Response To Radiation Cellular Ion Homeostasis Neuron Remodeling Bile Acid Secretion Oligopeptide Transport Cellular Chemical Homeostasis Negative Regulation Of Sodium Ion Transport Renal Absorption Regulation Of Proton Transport Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Phosphate Ion Homeostasis Ion Homeostasis Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Microvillus Assembly Microvillus Organization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Secretion Cellular Copper Ion Homeostasis Cellular Homeostasis Copper Ion Homeostasis Suckling Behavior Regulation Of Protein Kinase Activity Regulation Of Excretion Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Retinol Metabolic Process Regulation Of Kinase Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Chemical Homeostasis Bile Acid And Bile Salt Transport
Tagcloud ?		adipogenic alters amscs chondrogenic commitment deacetylases destabilizes foxo1 grown hdac hdac1 hdac11 hydroxamic hyper interferes lysate manipulation mechanistically mesenchymal multipotency multipotent nherf1 osteogenic perturbation pluripotent saha sirt7 suberoylanilide uncommitted
Tagcloud (Difference) ?		adipogenic alters amscs chondrogenic commitment deacetylases destabilizes foxo1 grown hdac hdac1 hdac11 hydroxamic hyper interferes lysate manipulation mechanistically mesenchymal multipotency multipotent nherf1 osteogenic perturbation pluripotent saha sirt7 suberoylanilide uncommitted
Tagcloud (Intersection) ?