RB1CC1 and LYPD3

Data Source:
BioGRID (two hybrid)

		RB1CC1	LYPD3
Description		RB1 inducible coiled-coil 1	LY6/PLAUR domain containing 3
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GO Annotations	Cellular Component	Phagophore Assembly Site Autophagosome Membrane Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Anchored Component Of Plasma Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Molecular Adaptor Activity	Laminin Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Cell-matrix Adhesion
Pathways		Macroautophagy	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)	Cotinine glucuronidation ( 25293881)
Interacting Genes		33 interacting genes: AZI2 BAP1 BLID COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TAX1BP1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1	17 interacting genes: AGR2 AGR3 AURKA BAG4 BRMS1 CASP8 CHEK2 CTRB1 ERBB2 IGF1R LSP1 PALB2 PPM1D PTPRJ RB1CC1 SMAD4 STK11
Entrez ID		9821	27076
HPRD ID		06019	10783
Ensembl ID		ENSG00000023287	ENSG00000124466
Uniprot IDs		Q8TDY2	B2RBR3 O95274
PDB IDs		6DCE 6GMA	6IOM 6ION
Enriched GO Terms of Interacting Partners?
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