LYPD3 and AGR3

Data Source:
HPRD (two hybrid)

		LYPD3	AGR3
Description		LY6/PLAUR domain containing 3	anterior gradient 3, protein disulphide isomerase family member
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Anchored Component Of Plasma Membrane	Endoplasmic Reticulum Intracellular Membrane-bounded Organelle
	Molecular Function	Laminin Binding	Dystroglycan Binding Protein Binding
	Biological Process	Cell-matrix Adhesion	Biological_process Negative Regulation Of Cell Death
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Cotinine glucuronidation ( 25293881)	Coffee consumption ( 31959922 29367735) Cutaneous malignant melanoma ( 32341527 26237428) Cutaneous squamous cell carcinoma ( 32041948) Diffusing capacity of carbon monoxide ( 30694715) Lung cancer in ever smokers ( 28604730) Melanoma ( 28212542) Refractive error ( 32231278) Residual cognition ( 28441426) Rosacea symptom severity ( 29771307) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432)
Interacting Genes		17 interacting genes: AGR2 AGR3 AURKA BAG4 BRMS1 CASP8 CHEK2 CTRB1 ERBB2 IGF1R LSP1 PALB2 PPM1D PTPRJ RB1CC1 SMAD4 STK11	35 interacting genes: AKT1 AP1B1 APC ASB10 BCAR3 CASP8 CATSPER1 CD46 CGRRF1 CNNM3 DAG1 DESI1 EDA2R ERLIN1 ESR2 FXYD3 KRTAP11-1 LIME1 LSM1 LYPD3 MMGT1 NRM NTAQ1 NUP62 PDZK1IP1 PRAF2 PTPN1 SGTA SGTB SPINT1 TGFB1 TIMMDC1 TMEM14B UBQLN1 UBQLN2
Entrez ID		27076	155465
HPRD ID		10783	16545
Ensembl ID		ENSG00000124466	ENSG00000173467
Uniprot IDs		B2RBR3 O95274	Q8TD06
PDB IDs		6IOM 6ION	3PH9
Enriched GO Terms of Interacting Partners?
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