LYPD3 and PPM1D

Data Source:
BioGRID (two hybrid)

		LYPD3	PPM1D
Description		LY6/PLAUR domain containing 3	protein phosphatase, Mg2+/Mn2+ dependent 1D
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Anchored Component Of Plasma Membrane	Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Laminin Binding	Protein Serine/threonine Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Mitogen-activated Protein Kinase Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Cell-matrix Adhesion	G2/M Transition Of Mitotic Cell Cycle DNA Methylation Chromatin Silencing Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation Protein Dephosphorylation Negative Regulation Of Cell Population Proliferation Cellular Response To Starvation Response To Radiation Response To Bacterium DNA Damage Response, Signal Transduction By P53 Class Mediator Peptidyl-threonine Dephosphorylation Negative Regulation Of Gene Expression, Epigenetic
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Transcriptional regulation by RUNX2
Drugs
Diseases
GWAS		Cotinine glucuronidation ( 25293881)	Blood urea nitrogen levels ( 31152163)
Interacting Genes		17 interacting genes: AGR2 AGR3 AURKA BAG4 BRMS1 CASP8 CHEK2 CTRB1 ERBB2 IGF1R LSP1 PALB2 PPM1D PTPRJ RB1CC1 SMAD4 STK11	24 interacting genes: BEX2 CASZ1 CHEK2 DIRAS3 DKK3 EPSTI1 ERRFI1 GLCE H3-3A H3C1 ITIH5 KDM1A LYPD3 MAPK11 MDM2 MRC2 NAT2 NCL NSD3 OSGIN1 RHOBTB2 RPL5 TP53 UBC
Entrez ID		27076	8493
HPRD ID		10783	05482
Ensembl ID		ENSG00000124466	ENSG00000170836
Uniprot IDs		B2RBR3 O95274	A0A0S2Z4M2 O15297
PDB IDs		6IOM 6ION
Enriched GO Terms of Interacting Partners?
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