RB1CC1 and GREB1

Data Source:
BioGRID (two hybrid)

		RB1CC1	GREB1
Description		RB1 inducible coiled-coil 1	growth regulating estrogen receptor binding 1
Image			No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Autophagosome Membrane Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex	Nucleoplasm Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Kinase Binding Molecular Adaptor Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Multicellular Organism Development
Pathways		Macroautophagy	Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Diisocyanate-induced asthma ( 25918132) Endometriosis ( 23104006 28537267) Gynecologic disease (multivariate analysis) ( 31488892) High density lipoprotein cholesterol levels ( 30108155) Inferior parietal cortex volume ( 31530798) Obesity-related traits ( 23251661) Uterine fibroids ( 30194396 31649266)
Interacting Genes		33 interacting genes: AZI2 BAP1 BLID COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TAX1BP1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1	11 interacting genes: BCAR3 CASP8 CDKN2C HMMR HRAS LSP1 PALB2 RB1CC1 SMAD4 TGFB1 XRCC3
Entrez ID		9821	9687
HPRD ID		06019	13611
Ensembl ID		ENSG00000023287	ENSG00000196208
Uniprot IDs		Q8TDY2	Q4ZG55
PDB IDs		6DCE 6GMA
Enriched GO Terms of Interacting Partners?
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