LYPD3 and BRMS1

Data Source:
BioGRID (two hybrid)

		LYPD3	BRMS1
Description		LY6/PLAUR domain containing 3	BRMS1 transcriptional repressor and anoikis regulator
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Anchored Component Of Plasma Membrane	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex
	Molecular Function	Laminin Binding	Protein Binding Histone Deacetylase Binding NF-kappaB Binding
	Biological Process	Cell-matrix Adhesion	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	HDACs deacetylate histones Potential therapeutics for SARS
Drugs
Diseases
GWAS		Cotinine glucuronidation ( 25293881)	Bipolar disorder ( 21926972 31043756)
Interacting Genes		17 interacting genes: AGR2 AGR3 AURKA BAG4 BRMS1 CASP8 CHEK2 CTRB1 ERBB2 IGF1R LSP1 PALB2 PPM1D PTPRJ RB1CC1 SMAD4 STK11	49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1
Entrez ID		27076	25855
HPRD ID		10783	05879
Ensembl ID		ENSG00000124466	ENSG00000174744
Uniprot IDs		B2RBR3 O95274	G5E9I4 Q9HCU9
PDB IDs		6IOM 6ION	2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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