RB1CC1 and MRC2

Data Source:
BioGRID (two hybrid)

		RB1CC1	MRC2
Description		RB1 inducible coiled-coil 1	mannose receptor C type 2
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GO Annotations	Cellular Component	Phagophore Assembly Site Autophagosome Membrane Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex	Focal Adhesion Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Molecular Adaptor Activity	Protein Binding Collagen Binding Carbohydrate Binding Signaling Receptor Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Osteoblast Differentiation Endocytosis Collagen Catabolic Process
Pathways		Macroautophagy	Cross-presentation of soluble exogenous antigens (endosomes) Cross-presentation of soluble exogenous antigens (endosomes)
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)	Blood protein levels ( 29875488) Diastolic blood pressure ( 28135244 30578418) Heel bone mineral density ( 30598549) Pulse pressure ( 28135244 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		33 interacting genes: AZI2 BAP1 BLID COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TAX1BP1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1	13 interacting genes: AKT1 BAG4 BRMS1 ESR2 MTDH NDEL1 PALB2 PAX2 PPM1D PTPN1 RAF1 RB1CC1 XRCC3
Entrez ID		9821	9902
HPRD ID		06019	10094
Ensembl ID		ENSG00000023287	ENSG00000011028
Uniprot IDs		Q8TDY2	Q9UBG0
PDB IDs		6DCE 6GMA	5AO5 5AO6 5E4K 5E4L 5EW6
Enriched GO Terms of Interacting Partners?
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