RB1CC1 and HBP1

Data Source:
BioGRID (two hybrid)

		RB1CC1	HBP1
Description		RB1 inducible coiled-coil 1	HMG-box transcription factor 1
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GO Annotations	Cellular Component	Phagophore Assembly Site Autophagosome Membrane Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex	Chromatin Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Protein Binding Protein Kinase Binding Molecular Adaptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Binding Protein Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Cell Cycle Arrest Wnt Signaling Pathway
Pathways		Macroautophagy
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)	Metabolite levels ( 23823483)
Interacting Genes		33 interacting genes: AZI2 BAP1 BLID COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TAX1BP1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1	19 interacting genes: ANKRD2 CASP8 CD2AP CREBBP EP300 ESR1 EWSR1 HDAC1 KIFBP RB1 RB1CC1 RBL2 SAP30 SIN3A SMAD1 TCF4 TMEM37 UBE2H ZNF212
Entrez ID		9821	26959
HPRD ID		06019	13634
Ensembl ID		ENSG00000023287	ENSG00000105856
Uniprot IDs		Q8TDY2	A0A024R722 B4DJ36 O60381
PDB IDs		6DCE 6GMA	2E6O 3QVE
Enriched GO Terms of Interacting Partners?
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