RB1CC1 and GLCE

Data Source:
BioGRID (two hybrid)

		RB1CC1	GLCE
Description		RB1 inducible coiled-coil 1	glucuronic acid epimerase
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GO Annotations	Cellular Component	Phagophore Assembly Site Autophagosome Membrane Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Molecular Adaptor Activity	Calcium Ion Binding Racemase And Epimerase Activity, Acting On Carbohydrates And Derivatives Protein Homodimerization Activity Heparosan-N-sulfate-glucuronate 5-epimerase Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Heparan Sulfate Proteoglycan Biosynthetic Process Heparin Biosynthetic Process
Pathways		Macroautophagy	HS-GAG biosynthesis
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)	Blood protein levels ( 30072576 29875488)
Interacting Genes		33 interacting genes: AZI2 BAP1 BLID COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TAX1BP1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1	11 interacting genes: BAG4 BCAR3 CASP8 ERBB2 ESR1 FBXO7 FGFR2 FGFR4 PAX2 PPM1D RB1CC1
Entrez ID		9821	26035
HPRD ID		06019	07020
Ensembl ID		ENSG00000023287	ENSG00000138604
Uniprot IDs		Q8TDY2	O94923
PDB IDs		6DCE 6GMA	6HZZ 6I01 6I02
Enriched GO Terms of Interacting Partners?
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