CLDN1 and PATJ

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		CLDN1	PATJ
Description		claudin 1	PATJ crumbs cell polarity complex component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Protein-containing Complex Tight Junction	Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Virus Receptor Activity Structural Molecule Activity Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Cell Adhesion Aging Establishment Of Blood-nerve Barrier Response To Toxic Substance Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Positive Regulation Of Cell Migration Response To Lipopolysaccharide Cell Junction Maintenance Maintenance Of Blood-brain Barrier Hyperosmotic Salinity Response Cell-cell Junction Organization Response To Ethanol Viral Entry Into Host Cell Protein Complex Oligomerization Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Establishment Of Skin Barrier Xenobiotic Transport Across Blood-nerve Barrier Response To Interleukin-18 Bicellular Tight Junction Assembly Cellular Response To Lead Ion Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Response To Dexamethasone Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Wound Healing Establishment Of Endothelial Intestinal Barrier Liver Regeneration Positive Regulation Of Bicellular Tight Junction Assembly Cellular Response To Butyrate	Establishment Of Apical/basal Cell Polarity Intracellular Signal Transduction Bicellular Tight Junction Assembly Tight Junction Assembly
Pathways		Tight junction interactions
Drugs
Diseases		Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome; Ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis (ILVASC)
GWAS		Optic disc size ( 31809533) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Autism spectrum disorders (social interaction) ( 32624584) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)
Interacting Genes		18 interacting genes: BRD4 CD69 CD79A CLDN3 DRG1 FNDC9 LNX1 MMP14 MMP2 MPDZ MS4A3 PATJ TJP1 TJP2 TJP3 TMEM179B TMEM9 WNK4	35 interacting genes: ADGRB1 ASIC3 CACNG2 CEP57L1 CINP CLDN1 CNKSR2 CRB3 CRIPT DDX18 GIPC2 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D HDAC7 HOMER1 KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 NECAB2 NLGN2 NRXN2 PALS1 PARD3 PAX6 PHYH PRDM16 SCN4A SCN5A TJP3
Entrez ID		9076	10207
HPRD ID		04760	04434
Ensembl ID		ENSG00000163347	ENSG00000132849
Uniprot IDs		A5JSJ9 O95832
PDB IDs
Enriched GO Terms of Interacting Partners?
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