PATJ and NECAB2

Data Source:
BioGRID (two hybrid)

		PATJ	NECAB2
Description		PATJ crumbs cell polarity complex component	N-terminal EF-hand calcium binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Plasma Membrane Axon Dendrite
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding A2A Adenosine Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding
	Biological Process	Establishment Of Apical/basal Cell Polarity Intracellular Signal Transduction Bicellular Tight Junction Assembly Tight Junction Assembly	Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Adenosine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Localization To Membrane
Pathways
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Autism spectrum disorders (social interaction) ( 32624584) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)	Body mass index (change over time) ( 25378290) Corneal astigmatism ( 29422769) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Rheumatoid arthritis ( 30891314)
Interacting Genes		35 interacting genes: ADGRB1 ASIC3 CACNG2 CEP57L1 CINP CLDN1 CNKSR2 CRB3 CRIPT DDX18 GIPC2 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D HDAC7 HOMER1 KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 NECAB2 NLGN2 NRXN2 PALS1 PARD3 PAX6 PHYH PRDM16 SCN4A SCN5A TJP3	89 interacting genes: ADORA2A AIMP2 BEX2 BEX3 BYSL C19orf25 C1orf109 C1orf216 CAGE1 CAPN3 CARD9 CCDC121 CCDC146 CCDC153 CCDC33 CCNK CDC37 CENPO CPEB2 DAXX DFFA DGCR6 DGCR6L DTNBP1 DYNC1I2 EAF2 EHHADH EIF4E2 EMILIN1 FAM161A FAM161B FANCG FXR2 GCC1 GOLGA2 GTPBP10 HAUS1 INPP1 INTS10 ISCU KANK2 KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 MSGN1 MTMR9 MYO15B MYPOP NECAB1 NEK6 NIP7 NOC4L NTAQ1 ODAD3 ODAD4 OIP5 PATJ PCM1 PICK1 POLR2C PRKAA2 PRPF18 PSMA1 PUS10 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SMARCD1 SNAPIN SOGA1 SSC5D TCEA2 TEX11 TRIM59 TRIML2 TTR USHBP1 USP7 VTA1 ZNF655
Entrez ID		10207	54550
HPRD ID		04434	13263
Ensembl ID		ENSG00000132849	ENSG00000103154
Uniprot IDs			Q7Z6G3
PDB IDs
Enriched GO Terms of Interacting Partners?
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