PATJ and ASIC3

Data Source:
HPRD (in vitro, two hybrid)

		PATJ	ASIC3
Description		PATJ crumbs cell polarity complex component	acid sensing ion channel subunit 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Cation Channel Activity Sodium Channel Activity Ligand-gated Sodium Channel Activity Enterobactin Transmembrane Transporter Activity Acid-sensing Ion Channel Activity
	Biological Process	Establishment Of Apical/basal Cell Polarity Intracellular Signal Transduction Bicellular Tight Junction Assembly Tight Junction Assembly	Signal Transduction Sensory Perception Response To Heat Response To Acidic PH Ion Transmembrane Transport Sodium Ion Transmembrane Transport Enterobactin Transport Sensory Perception Of Sour Taste Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain
Pathways			Stimuli-sensing channels
Drugs			Agmatine
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Autism spectrum disorders (social interaction) ( 32624584) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)	Eyebrow thickness ( 26926045)
Interacting Genes		35 interacting genes: ADGRB1 ASIC3 CACNG2 CEP57L1 CINP CLDN1 CNKSR2 CRB3 CRIPT DDX18 GIPC2 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D HDAC7 HOMER1 KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 NECAB2 NLGN2 NRXN2 PALS1 PARD3 PAX6 PHYH PRDM16 SCN4A SCN5A TJP3	9 interacting genes: ASIC2 CSNK2A1 DLG4 GOPC LIN7B MAGI1 PATJ PRKACA STOM
Entrez ID		10207	9311
HPRD ID		04434	10626
Ensembl ID		ENSG00000132849	ENSG00000213199
Uniprot IDs			A0A090N7X8 A0A090N8Q1 A0A090N8Z6 Q9UHC3
PDB IDs
Enriched GO Terms of Interacting Partners?
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