CLDN1 and CD69

Data Source:
BioGRID (two hybrid)

		CLDN1	CD69
Description		claudin 1	CD69 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Protein-containing Complex Tight Junction	Integral Component Of Plasma Membrane External Side Of Plasma Membrane Protein-containing Complex
	Molecular Function	Virus Receptor Activity Structural Molecule Activity Protein Binding Identical Protein Binding	Transmembrane Signaling Receptor Activity Calcium Ion Binding Protein Binding Carbohydrate Binding Identical Protein Binding
	Biological Process	Cell Adhesion Aging Establishment Of Blood-nerve Barrier Response To Toxic Substance Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Positive Regulation Of Cell Migration Response To Lipopolysaccharide Cell Junction Maintenance Maintenance Of Blood-brain Barrier Hyperosmotic Salinity Response Cell-cell Junction Organization Response To Ethanol Viral Entry Into Host Cell Protein Complex Oligomerization Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Establishment Of Skin Barrier Xenobiotic Transport Across Blood-nerve Barrier Response To Interleukin-18 Bicellular Tight Junction Assembly Cellular Response To Lead Ion Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Response To Dexamethasone Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Wound Healing Establishment Of Endothelial Intestinal Barrier Liver Regeneration Positive Regulation Of Bicellular Tight Junction Assembly Cellular Response To Butyrate
Pathways		Tight junction interactions
Drugs
Diseases		Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome; Ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis (ILVASC)
GWAS		Optic disc size ( 31809533) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)	Lymphocyte counts ( 29403010 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Medication use (thyroid preparations) ( 31015401) Monocyte count ( 32888494) Multiple sclerosis ( 24076602) Neutrophil percentage of white cells ( 32888494 27863252) Type 1 diabetes ( 25751624 19430480) White blood cell count ( 32888494)
Interacting Genes		18 interacting genes: BRD4 CD69 CD79A CLDN3 DRG1 FNDC9 LNX1 MMP14 MMP2 MPDZ MS4A3 PATJ TJP1 TJP2 TJP3 TMEM179B TMEM9 WNK4	14 interacting genes: ATP6V0C BRICD5 CLDN1 EBP MAL NINJ2 PMP22 RPRM SLC35B2 SMARCB1 STRIT1 TMEM190 TSPO2 UPK1B
Entrez ID		9076	969
HPRD ID		04760	00119
Ensembl ID		ENSG00000163347	ENSG00000110848
Uniprot IDs		A5JSJ9 O95832	Q07108 Q53ZX0
PDB IDs			1E87 1E8I 1FM5 3CCK 3HUP
Enriched GO Terms of Interacting Partners?
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