ADAM33 and PLEKHO1

		ADAM33	PLEKHO1
Description		ADAM metallopeptidase domain 33	pleckstrin homology domain containing O1
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GO Annotations	Cellular Component	Integral Component Of Membrane	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane
	Molecular Function	Metalloendopeptidase Activity Zinc Ion Binding	Protein Binding
	Biological Process	Proteolysis	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis
Pathways
Drugs
Diseases		Asthma
GWAS		Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) White blood cell count ( 32888494)	Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		33 interacting genes: AQP9 ASGR2 ATXN7 BTNL9 CD3E CLDN2 CLEC7A CREB3L1 CYB5R3 EPGN FCGR2A GGT6 HIBADH KIR3DL3 LMNA MUC1 NCR1 OPRM1 PLEKHO1 SEC11A SGCB SLC22A23 SLC30A2 SLC35E2A SLC4A1 SPINT1 STOML3 TMEM106C TMEM14B TMEM237 TNFSF14 UBQLN4 VMA21	32 interacting genes: ADAM33 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C4orf3 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB IFI35 LRP10 MMD NAPB PSMC5 RPS20 SMAD5 SMURF1 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1
Entrez ID		80332	51177
HPRD ID		06173	12217
Ensembl ID		ENSG00000149451	ENSG00000023902
Uniprot IDs		A2A2L3 Q9BZ11	Q53GL0 Q5T4P9
PDB IDs		1R54 1R55	3AA1
Enriched GO Terms of Interacting Partners?
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