PLEKHO1 and NAPB

Data Source:
BioGRID (two hybrid)

		PLEKHO1	NAPB
Description		pleckstrin homology domain containing O1	NSF attachment protein beta
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane	Vacuolar Membrane SNARE Complex Synapse Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Exosome
	Molecular Function	Protein Binding	Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding
	Biological Process	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis	Intracellular Protein Transport Regulation Of Synaptic Vesicle Priming Synaptic Transmission, Glutamatergic SNARE Complex Disassembly
Pathways			COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Factor VII activity ( 30642921)
Interacting Genes		32 interacting genes: ADAM33 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C4orf3 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB IFI35 LRP10 MMD NAPB PSMC5 RPS20 SMAD5 SMURF1 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1	31 interacting genes: ALOX5AP ARL6IP1 BET1 CISD2 CLEC10A CREB3L1 DGAT2L6 FAM209A GJB5 HSD17B13 KCNN3 LEUTX PLEKHO1 SDCBP SIGLEC5 SNAP23 SNAP29 STX16 STX19 STX1A STX1B STX2 STX3 STX4 STX5 STX6 SYT1 SYT2 TAF1B TFEC TMEM139
Entrez ID		51177	63908
HPRD ID		12217	17627
Ensembl ID		ENSG00000023902	ENSG00000125814
Uniprot IDs		Q53GL0 Q5T4P9	A0A087WZQ7 Q9H115
PDB IDs		3AA1
Enriched GO Terms of Interacting Partners?
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