ADAM33 and SLC30A2

Data Source:
BioGRID (two hybrid)

		ADAM33	SLC30A2
Description		ADAM metallopeptidase domain 33	solute carrier family 30 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Metalloendopeptidase Activity Zinc Ion Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Identical Protein Binding
	Biological Process	Proteolysis	Response To Zinc Ion Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport
Pathways			Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases		Asthma
GWAS		Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		33 interacting genes: AQP9 ASGR2 ATXN7 BTNL9 CD3E CLDN2 CLEC7A CREB3L1 CYB5R3 EPGN FCGR2A GGT6 HIBADH KIR3DL3 LMNA MUC1 NCR1 OPRM1 PLEKHO1 SEC11A SGCB SLC22A23 SLC30A2 SLC35E2A SLC4A1 SPINT1 STOML3 TMEM106C TMEM14B TMEM237 TNFSF14 UBQLN4 VMA21	66 interacting genes: ABHD16A ADAM33 AQP2 AQP6 ATP13A1 C5orf46 CCL4 CCL4L2 CD40 CD52 CD79A CD99L2 CPLX4 CREB3 CTSA CYB561D2 EBAG9 EMP3 EVI2B F11R FAM174A FDPS FFAR2 FXYD3 FXYD6 GALNT15 GJA5 GJB2 GJB5 GLB1 GOLT1A GPR161 GPR42 GPRC5D HGFAC KASH5 KCNN4 LMNA LTA LYVE1 MS4A13 NDUFAF1 NRM OPRM1 PCNX2 PLPPR1 PVR SEC22A SELL SERPING1 SLC10A6 SLC16A2 SLC18A1 SLC38A7 SLC39A2 SLC7A1 SLC7A8 TAS2R5 TM4SF18 TMEM107 TMEM52B TMEM60 TMEM86A TNFRSF12A TRARG1 YIPF2
Entrez ID		80332	7780
HPRD ID		06173	18057
Ensembl ID		ENSG00000149451	ENSG00000158014
Uniprot IDs		A2A2L3 Q9BZ11	Q9BRI3
PDB IDs		1R54 1R55
Enriched GO Terms of Interacting Partners?
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