ADAM33 and SGCB

Data Source:
BioGRID (two hybrid)

		ADAM33	SGCB
Description		ADAM metallopeptidase domain 33	sarcoglycan beta
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytoplasm Cytoskeleton Integral Component Of Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Sarcolemma
	Molecular Function	Metalloendopeptidase Activity Zinc Ion Binding	Protein Binding
	Biological Process	Proteolysis	Muscle Organ Development Muscle Fiber Development Cardiac Muscle Cell Development Vascular Associated Smooth Muscle Cell Development
Pathways
Drugs
Diseases		Asthma	Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)
GWAS		Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		33 interacting genes: AQP9 ASGR2 ATXN7 BTNL9 CD3E CLDN2 CLEC7A CREB3L1 CYB5R3 EPGN FCGR2A GGT6 HIBADH KIR3DL3 LMNA MUC1 NCR1 OPRM1 PLEKHO1 SEC11A SGCB SLC22A23 SLC30A2 SLC35E2A SLC4A1 SPINT1 STOML3 TMEM106C TMEM14B TMEM237 TNFSF14 UBQLN4 VMA21	22 interacting genes: ADAM33 ADRA1A APOL3 BRICD5 CLEC7A CMTM5 EHHADH HTR2C LTB4R2 MAL MGST2 NINJ1 PTTG1IP SGCA SGCD SGCG SGCZ SLC52A1 SMIM3 TMEM11 TNF TRIM63
Entrez ID		80332	6443
HPRD ID		06173	02942
Ensembl ID		ENSG00000149451	ENSG00000163069
Uniprot IDs		A2A2L3 Q9BZ11	Q16585 Q5U0N0
PDB IDs		1R54 1R55
Enriched GO Terms of Interacting Partners?
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