PLEKHO1 and C10orf88

Data Source:
BioGRID (two hybrid)

		PLEKHO1	C10orf88
Description		pleckstrin homology domain containing O1	chromosome 10 open reading frame 88
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane	Cytoplasm Mitochondrion
	Molecular Function	Protein Binding	Protein Binding ATPase Activity Identical Protein Binding
	Biological Process	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Apolipoprotein B levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) LDL cholesterol ( 30275531) LDL cholesterol levels ( 32203549 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Mean reticulocyte volume ( 32888494) Red cell distribution width ( 32888494 28957414)
Interacting Genes		32 interacting genes: ADAM33 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C4orf3 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB IFI35 LRP10 MMD NAPB PSMC5 RPS20 SMAD5 SMURF1 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1	11 interacting genes: APP CLTC HSF2BP IMMT LNX1 LNX2 MEOX2 PKNOX2 PLEKHO1 TRIM55 TRIM63
Entrez ID		51177	80007
HPRD ID		12217	18531
Ensembl ID		ENSG00000023902	ENSG00000119965
Uniprot IDs		Q53GL0 Q5T4P9	Q9H8K7
PDB IDs		3AA1
Enriched GO Terms of Interacting Partners?
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