ADAM33 and VMA21

		ADAM33	VMA21
Description		ADAM metallopeptidase domain 33	vacuolar ATPase assembly factor VMA21
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Lysosome Vacuole Endoplasmic Reticulum Membrane ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Metalloendopeptidase Activity Zinc Ion Binding	Protein Binding
	Biological Process	Proteolysis	Regulation Of ATPase Activity Vacuolar Proton-transporting V-type ATPase Complex Assembly
Pathways
Drugs
Diseases		Asthma
GWAS		Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		33 interacting genes: AQP9 ASGR2 ATXN7 BTNL9 CD3E CLDN2 CLEC7A CREB3L1 CYB5R3 EPGN FCGR2A GGT6 HIBADH KIR3DL3 LMNA MUC1 NCR1 OPRM1 PLEKHO1 SEC11A SGCB SLC22A23 SLC30A2 SLC35E2A SLC4A1 SPINT1 STOML3 TMEM106C TMEM14B TMEM237 TNFSF14 UBQLN4 VMA21	29 interacting genes: ABHD16A ADAM33 AQP6 ARL6IP1 ATP13A1 ATP6V0B BNIP1 CDIPT CLEC12B DAGLA HMOX2 INSIG2 LHFPL5 LYPD6B NINJ2 NIPAL3 ORMDL1 PLLP RTP2 SCD SLC25A46 SLC35E4 TECR THSD7A TMEM107 TMEM60 VAMP2 YIF1A YIPF1
Entrez ID		80332	203547
HPRD ID		06173	18578
Ensembl ID		ENSG00000149451	ENSG00000160131
Uniprot IDs		A2A2L3 Q9BZ11	Q3ZAQ7
PDB IDs		1R54 1R55
Enriched GO Terms of Interacting Partners?
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