ERMP1 and PEX12

Data Source:
BioGRID (two hybrid)

		ERMP1	PEX12
Description		endoplasmic reticulum metallopeptidase 1	peroxisomal biogenesis factor 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Peroxisomal Importomer Complex
	Molecular Function	Protein Binding Metallopeptidase Activity Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding
	Biological Process	Proteolysis Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress	Protein Monoubiquitination Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination
Pathways			E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import
Drugs
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Asthma ( 31959851 31619474) Blond vs. brown/black hair color ( 30531825) Waist-hip ratio ( 28552196)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		37 interacting genes: AQP2 AQP6 ATP1B4 BCL2L13 BSCL2 CD200R1 CLDN5 CLDN7 CLDN9 CLEC2D CREB3L1 ERVFRD-1 FAM209A FNDC9 GJA8 GPR42 GPRC5D HHLA2 HIBADH IER3IP1 IFNGR2 KCNN3 KLRC1 LYPD5 MR1 PDCD1LG2 PEX12 RHCG SLC13A4 SLC22A23 SLC23A2 SLC7A14 SPAG4 SSMEM1 TMEM237 TMEM45A TMEM80	36 interacting genes: ACSL5 ADIPOQ BNIP2 BTN2A2 C5orf46 CLDN10 COL8A2 CXCL16 CYBC1 DNAJC30 ERMP1 FA2H FKBP8 FXYD6 GJB2 IER3IP1 MARCHF2 MGLL NKG7 NRM PEX10 PEX19 PEX5 PNLIPRP1 PTPN9 RBFA SEC22A SEC61G SMCO4 SRGN STX8 THSD7B TMEM11 TMEM222 TREX1 TTPA
Entrez ID		79956	5193
HPRD ID		17227	03455
Ensembl ID		ENSG00000099219	ENSG00000108733
Uniprot IDs		Q6ZMD3 Q7Z2K6	O00623
PDB IDs
Enriched GO Terms of Interacting Partners?
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