PEX12 and TMEM11

Data Source:
BioGRID (two hybrid)

		PEX12	TMEM11
Description		peroxisomal biogenesis factor 12	transmembrane protein 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Peroxisomal Importomer Complex	Mitochondrion Integral Component Of Plasma Membrane Integral Component Of Mitochondrial Inner Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding	Molecular_function Protein Binding
	Biological Process	Protein Monoubiquitination Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination	Mitochondrion Organization Inner Mitochondrial Membrane Organization
Pathways		E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import	Cristae formation
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Body mass index ( 26426971) Metabolite levels ( 23823483)
Interacting Genes		36 interacting genes: ACSL5 ADIPOQ BNIP2 BTN2A2 C5orf46 CLDN10 COL8A2 CXCL16 CYBC1 DNAJC30 ERMP1 FA2H FKBP8 FXYD6 GJB2 IER3IP1 MARCHF2 MGLL NKG7 NRM PEX10 PEX19 PEX5 PNLIPRP1 PTPN9 RBFA SEC22A SEC61G SMCO4 SRGN STX8 THSD7B TMEM11 TMEM222 TREX1 TTPA	53 interacting genes: ARL13B BDKRB2 BIK BNIP3 BNIP3L CCDC70 CCR4 CD79A CLDN7 CLN8 CREB3L1 CYB561 CYB5D2 DRD2 EBP ELOVL4 FAM174A FAM209A FAM210B FATE1 FFAR2 GJB4 GORAB KASH5 LEPROTL1 LMNA MRM1 MSMO1 MTIF3 MUC1 NDUFS3 OTX2 PDZK1IP1 PEX12 RETREG3 RIC3 RNASEH1 SCMH1 SGCB SLC10A6 SLC30A8 SUSD3 SUV39H1 TEX29 TMEM106C TMEM14B TMEM205 TMEM237 TMEM88 TMIE TMPRSS2 TNFSF14 YIPF6
Entrez ID		5193	8834
HPRD ID		03455	12680
Ensembl ID		ENSG00000108733	ENSG00000178307
Uniprot IDs		O00623	P17152
PDB IDs
Enriched GO Terms of Interacting Partners?
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