ERMP1 and SLC22A23

Data Source:
BioGRID (two hybrid)

		ERMP1	SLC22A23
Description		endoplasmic reticulum metallopeptidase 1	solute carrier family 22 member 23
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Integral Component Of Membrane
	Molecular Function	Protein Binding Metallopeptidase Activity Metal Ion Binding	Protein Binding Transmembrane Transporter Activity
	Biological Process	Proteolysis Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress	Ion Transport Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474) Blond vs. brown/black hair color ( 30531825) Waist-hip ratio ( 28552196)	Antipsychotic drug-induced QTc interval prolongation ( 20921969) Bone mineral density (femoral neck) in inflammatory bowel disease ( 29603369) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) ( 21221126) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting insulin (dietary factor interaction) ( 24204828) General cognitive ability ( 29844566) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean platelet volume ( 32888494 27863252) Nicotine dependence ( 28440896) Obesity-related traits ( 23251661) Primary biliary cholangitis ( 28425483) Red cell distribution width ( 32888494 27863252 28957414) Refractive error ( 32231278) Survival in rectal cancer ( 25866641)
Interacting Genes		37 interacting genes: AQP2 AQP6 ATP1B4 BCL2L13 BSCL2 CD200R1 CLDN5 CLDN7 CLDN9 CLEC2D CREB3L1 ERVFRD-1 FAM209A FNDC9 GJA8 GPR42 GPRC5D HHLA2 HIBADH IER3IP1 IFNGR2 KCNN3 KLRC1 LYPD5 MR1 PDCD1LG2 PEX12 RHCG SLC13A4 SLC22A23 SLC23A2 SLC7A14 SPAG4 SSMEM1 TMEM237 TMEM45A TMEM80	17 interacting genes: ADAM33 ADIPOQ CBLIF CLCA4 CLN6 CNIH1 ERMP1 KRTAP1-3 KRTAP10-8 KRTAP5-9 MEOX2 NOTCH2NLA OLFM4 PSMA3 PTTG1IP UPK2 WFDC2
Entrez ID		79956	63027
HPRD ID		17227	12904
Ensembl ID		ENSG00000099219	ENSG00000137266
Uniprot IDs		Q6ZMD3 Q7Z2K6	A1A5C7 Q9UFY2
PDB IDs
Enriched GO Terms of Interacting Partners?
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